841302-24-7

Basic information

• Product Name: Hydroxy Saxagliptin
• Synonyms: Hydroxy Saxagliptin;(1S,3S,5S)-2-[(2S)-2-aMino-2-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-Azabicyclo[3.1.0]hexane-3-carbonitrile;BMS 510849;5-Hydroxy Saxagliptin;2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2- (3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3S,5S)-;(1S,3R,5S)-2-[(2S)-2-amino-2-[(3R,5S)-3,5-dihydroxy-1-adamantyl]acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;Saxagliptin Impurity 24;5-Hydroxy Saxagliptin Hydrochloride Labeled 15N,d2
• CAS NO: 841302-24-7
• Molecular Formula: C18H25N3O3
• Molecular Weight: 331.4094
• Product Categories: Amines;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 841302-24-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 589.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.43±0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly), DCM
• PKA: 14.39±0.60(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: Hydroxy Saxagliptin(CAS DataBase Reference)
• NIST Chemistry Reference: Hydroxy Saxagliptin(841302-24-7)
• EPA Substance Registry System: Hydroxy Saxagliptin(841302-24-7)

Safety Data

• Hazardous Substances Data: 841302-24-7(Hazardous Substances Data)

Usage

Description

Hydroxy Saxagliptin is a metabolite of Saxagliptin (S143500), a medication used for the treatment of type 2 diabetes. It is formed as a result of the metabolism of Saxagliptin in the body.

Uses

Used in Pharmaceutical Industry:
Hydroxy Saxagliptin is used as a metabolite of Saxagliptin for the treatment of type 2 diabetes. It plays a role in the body's metabolism of Saxagliptin, contributing to the overall effectiveness of the medication in managing blood sugar levels.

Upstream product

• 1564265-93-5 saxagliptin 

Relevant articles and documents

EX VIVO METHODS FOR PREDICTING AND CONFIRMING IN VIVO METABOLISM OF PHARMACEUTICALLY ACTIVE COMPOUNDS

Methods and compositions for the catalytic oxidation of pharmaceutically active compounds, and more particularly to ex vivo methods for predicting in vivo metabolism of pharmaceutically active compounds, including predicting in vivo interaction between two or more pharmaceutically active compounds.