84141-26-4Relevant academic research and scientific papers
The design and development of potent small molecules as anticancer agents targeting EGFR TK and tubulin polymerization
Ihmaid, Saleh,Ahmed, Hany E. A.,Zayed, Mohamed F.
, (2018/02/09)
Some novel anthranilate diamides derivatives 4a–e, 6a–c and 9a–d were designed and synthesized to be evaluated for their in vitro anticancer activity. Structures of all newly synthesized compounds were confirmed by infra-red (IR), high-resolution mass (HR
A New Synthesis of 2-Aryl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones
Reddy, Ch. K.,Reddy, P. S. N.,Ratnam, C. V.
, p. 902 - 904 (2007/10/02)
The reaction of 2-aryl-3,1-benzoxazine-4-ones (1) and hydrazine hydrate in refluxing xylene yields 2-aryl-3,4-dihydro-5H-1,3,4-benzotriazepin-5-ones in 55-74percent yield.In basic conditions this reaction, however, gives 2-aryl-3-aminoquinazolin-4(3H)-one
