84161-62-6

Upstream product

• 24652-74-2 methyl 6-phenoxyacetamidopenicillanate-1β-oxide 
• 81651-28-7 (2R,3S)-3-phenoxyacetamido-1-(1'-methyloxycarbonyl-2'-methyl-prop-1'-enyl)-4-oxoazetidine-2-sulphinic acid 
• 507-09-5 tiolacetic acid 
• 108-24-7 acetic anhydride 
• 41625-69-8 methyl 6α-methoxy-6β-phenoxyacetamidopenicillanate-1β-oxide 

Downstream Products

• 117509-09-8 4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinone 
• 117509-08-7 N-methoxalyl 4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinone 
• 84181-47-5 [(2R,3S)-2-Acetylsulfanyl-3-methoxy-4-oxo-3-(2-phenoxy-acetylamino)-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid methyl ester 
• 84161-73-9 p-nitrobenzyl (4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)triphenylphosphoranylidene acetate 
• 84161-72-8 p-nitrobenzyl (5R) 6S-methoxy-2-methyl-6-phenoxyacetamidopenem-3-carboxylate 

Relevant academic research and scientific papers

CONTRASTING THERMAL BEHAVIOUR OF DIASTEREOISOMERIC 4-ACETYLTHIO-3-ACYLAMINO-1-(α-TRIPHENYLPHOSPHORANYLIDENE)ALKOXYCARBONYLMETHYLAZETIDIN-2-ONES

Under conditions in which cis isomers of the title compounds are converted into 6β-acylamino-2-methylpenem-3-carboxylates, trans isomers afford thiazole-4-carboxylates and 2-alkyloxazolin-5-ones.

Synthesis and Reactivity of 6α-Methoxy-2-methyl-6β-phenoxyacetamido-penem-3-carboxylates

Representatives of the title compounds have been prepared from phenoxymethylpenicillinic acid; the β-lactam linkage of these compounds is exceptionally reactive.