84170-99-0Relevant academic research and scientific papers
Enantioselective synthesis of α-tri- and α-tetrasubstituted allylsilanes by copper-catalyzed asymmetric allylic substitution of allyl phosphates with silylboronates
Takeda, Momotaro,Shintani, Ryo,Hayashi, Tamio
, p. 5007 - 5017 (2013/07/11)
A copper/N-heterocyclic carbene-catalyzed asymmetric allylic substitution of allyl phosphates with a silylboronate has been developed to give highly enantioenriched allylsilanes. High regioselectivity has been achieved by employing NaOH as the base, and this catalyst system is effective for both γ-mono- and disubstituted allyl phosphates.
Enantioselective Allylation of Aldehydes with an Optically Active Allylsilane
Hayashi, Tamio,Konishi, Mitsuo,Kumada, Makoto
, p. 281 - 282 (2007/10/02)
Reaction of aldehydes with an optically active allylsilane, (R)-3-phenyl-3-(trimethylsilyl)propene, in the presence of titanium chloride has been found to proceed with high enantioselectivity to produce optically active homoallylic alcohols of up to 91per
