84174-31-2Relevant academic research and scientific papers
A Comparison of Some Friedel-Crafts and Grignard Reactions of Optically Active Phenyloxirane
Taylor, Stephen K.,Haberkamp, William C.,Brooks, Dee W.,Whittern, David N.
, p. 1745 - 1747 (2007/10/02)
The Friedel-Crafts reactions of optically active phenyloxirane with toluene and anisole were examined for stereospecifity.The enantiomeric ratios of the diarylethanol products were determined and compared to those of the same products obtained from the reaction of p-tolyl and p-methoxyphenyl Grignard reagents with optically active phenyloxirane.The p-tolyl Grignard and Friedel-Crafts products gave similar enantiomeric ratios (approximately 64:36 and 60:40, respectively).However, in the p-methoxyphenyl products from the Grignard and Friedel-Crafts reactions, different enantiomers predominated (ratios 33:67 and 62:38, respectively).
