84184-56-5

Basic information

• Product Name: 2-Propen-1-ol, 3-[4-(methoxymethoxy)phenyl]-, (2E)-
• CAS NO: 84184-56-5
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol File: 84184-56-5.mol

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-ol, 3-[4-(methoxymethoxy)phenyl]-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-ol, 3-[4-(methoxymethoxy)phenyl]-, (2E)-(84184-56-5)
• EPA Substance Registry System: 2-Propen-1-ol, 3-[4-(methoxymethoxy)phenyl]-, (2E)-(84184-56-5)

Safety Data

• Hazardous Substances Data: 84184-56-5(Hazardous Substances Data)

Upstream product

• 84184-55-4 methyl trans-3-(4-methoxymethoxyphenyl)propenoate 
• 7400-08-0 p-Coumaric Acid 

Downstream Products

• 84184-57-6 (E)-3-[4-(methoxymethoxy)phenyl]acrylaldehyde 
• 953758-43-5 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-3-heptanone 
• 130233-83-9 1,7-bis(4'-hydroxyphenyl)-3-heptanone 
• 1083200-79-6 (E)-1,7-bis(4-hydroxyphenyl)hept-1-en-3-one 
• 84184-58-7 methyl boninenalate ethylene acetal 
• 84184-59-8 boninenal ethylene acetal 
• 73213-61-3 methyl boninenalate 
• 2538-87-6 trans-p-hydroxycinnamaldehyde 
• 850176-72-6 3-(4-methoxymethoxyphenyl)propenyl 3-(3,4-dimethoxymethoxyphenyl)allylate 
• 850176-71-5 3-(4-methoxymethoxyphenyl)propenyl 3-(4-methoxymethoxyphenyl)allylate 

Relevant articles and documents

Synthesis of natural and non-natural curcuminoids and their neuroprotective activity against glutamate-induced oxidative stress in HT-22 cells

A strategy for the synthesis of natural and non-natural 5-deoxy-6,7-dihydrocurcuminoids (diarylheptanoids) was developed for the preparation of 14 compounds with varying aromatic substituent patterns and a different functionality in the aliphatic seven-carbon chain. The in vitro protective activity against glutamate-induced neuronal cell death was examined in the murine hippocampal cell line HT-22 to find structural motifs responsible for neuroprotective effects in vitro. Among the tested compounds the ferulic acid-like unit, present in the structures of (E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-1-en-3-one (5) and (E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hept-1-en-3-one (7), appeared to be an important feature for protection against glutamate-induced neurotoxicity. Both compounds demonstrated significant neuroprotective activity in a concentration range between 1 and 25 ～M without showing toxic effects in a cytotoxicity assay with HT-22 cells. Furthermore, (E)-1,7-bis(3,4-dihydroxyphenyl)hept-1-en-3-one (9), exhibiting a caffeic acid-like structural motif, displayed a neuroprotective activity at a nontoxic concentration of 25 ～M. In contrast, (1E,6E)-1,7-bis(3,4-dihydroxyphenyl)hepta-1,6-diene-3,5-dione (4, di-O-demethylcurcumin) showed mainly cytotoxic effects. A corresponding single-ring analogue that contains the ferulic acid-like unit as an enone was not active.

Studies on the Chemical Constituents of Rutaceous Plants. Part 45. Novel Phenyl Propanoids: Cuspidiol, Boninenal, and Methyl Boninenalate

Cuspidiol, boninenal, and methyl boninenalate were established as having the structures 3-phenyl>propanol (1), (E)-3-phenyl>propenal (2), and (E)-3-phenyl>propenal (3) respectively.The three compounds were also independently synthesized.