842117-37-7Relevant articles and documents
An improved synthesis of hydroxyindoles
Lerman, Lena,Weinstock-Rosin, Marta,Nudelman, Abraham
, p. 3043 - 3046 (2007/10/03)
An improved synthetic procedure for the synthesis of 6- and 7-hydroxyindoles is described. In this method, the addition of two chlorine atoms in 1-benzyloxy-4,5-dichloro-2-nitrobenzene (3) and 1-benzyloxy-2,6- dichloro-3-nitrobenzene (9) facilitated the subsequent cyanomethylation step to give substituted cyanomethyl-dichloronitrobenzenes 4 and 10, leading to an overall increase in the yield of the hydroxyindoles 6 and 12.