842136-72-5 Usage
Molecular Structure
1H-Pyrazole-4-methanol, a-(5-bromo-2-chlorophenyl)-1-phenylcontains a pyrazole ring, a phenyl group, and a bromo-chloro substituent.
Biological Activity
The compound may exhibit biological activity, making it potentially useful in the pharmaceutical industry.
Industrial Applications
It has potential applications in the agrochemical industry as well.
Building Block for Synthesis
The compound is a valuable building block for the synthesis of various molecules, including pharmaceuticals, pesticides, and other bioactive compounds.
Unique Structure and Reactivity
The compound's unique structure and reactivity make it an important intermediate in organic synthesis and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 842136-72-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,2,1,3 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 842136-72:
(8*8)+(7*4)+(6*2)+(5*1)+(4*3)+(3*6)+(2*7)+(1*2)=155
155 % 10 = 5
So 842136-72-5 is a valid CAS Registry Number.
842136-72-5Relevant academic research and scientific papers
Discovery of canagliflozin, a novel C-glucoside with thiophene ring, as sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes mellitus (1)
Nomura, Sumihiro,Sakamaki, Shigeki,Hongu, Mitsuya,Kawanishi, Eiji,Koga, Yuichi,Sakamoto, Toshiaki,Yamamoto, Yasuo,Ueta, Kiichiro,Kimata, Hirotaka,Nakayama, Keiko,Tsuda-Tsukimoto, Minoru
supporting information; experimental part, p. 6355 - 6360 (2010/11/03)
We discovered that C-glucosides 4 bearing a heteroaromatic ring formed metabolically more stable inhibitors for sodium-dependent glucose cotransporter 2 (SGLT2) than the O-glucoside, 2 (T-1095). A novel thiophene derivative 4b-3 (canagliflozin) was a highly potent and selective SGLT2 inhibitor and showed pronounced anti-hyperglycemic effects in high-fat diet fed KK (HF-KK) mice.
