842167-68-4

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 842167-67-3 1-bromo-4-fluoro-2-(methoxymethyl)benzene 
• 94569-84-3 2-bromo-5-fluorobenzaldehyde 
• 202865-66-5 2-bromo-5-fluorobenzyl alcohol 

Downstream Products

• 842167-70-8 1-(2,2-dibromovinyl)-4-fluoro-2-(methoxymethyl)benzene 
• 842167-56-0 {2-[2-(3-butenyl)-4-fluorophenyl]ethynyl}trimethylsilane 
• 842167-55-9 {2-[4-fluoro-2-(methoxymethyl)phenyl]ethynyl}trimethylsilane 
• 842167-61-7 2-(3-butenyl)-1-ethynyl-4-fluorobenzene 

Relevant academic research and scientific papers

Copper-catalyzed allylations of zirconocene intermediates generated from o-alkenyl or o-alkynylbenzyl ether derivatives and zirconocene-butene complex

(Chemical Equation Presented) o-Alkenyl or alkynyl benzylzirconocene intermediate, which was readily generated by the reaction of 2-alkoxymethyl-styrene or 2-alkoxymethyl-1-(trimethylsilylethynyl)-benzene derivative with zirconocene-butene complex (Negishi reagent, "Cp 2Zr"), reacted with allyl or propargyl halides in the presence of a catalytic amount of CuCl to give allylation or allenylation products. Conversion to Dane's diene, which is a key intermediate for estrone synthesis, was efficiently carried out by enyne olefin metathesis of the allylation products.