84224-83-9Relevant academic research and scientific papers
Redox-active benzimidazolium sulfonamides as cationic thiolating reagents for reductive cross-coupling of organic halides
Zhang, Weigang,Huang, Mengjun,Zou, Zhenlei,Wu, Zhengguang,Ni, Shengyang,Kong, Lingyu,Zheng, Youxuan,Wang, Yi,Pan, Yi
, p. 2509 - 2514 (2021/03/01)
Redox-active benzimidazolium sulfonamides as thiolating reagents have been developed for reductive C-S bond coupling. The IMDN-SO2R reagent provides a bench-stable cationic precursor to generate a portfolio of highly active N-S intermediates, which can be successfully applied in cross-electrophilic coupling with various organic halides. The employment of an electrophilic sulfur source solved the problem of catalyst deactivation and avoided odorous thiols, featuring practical conditions, broad substrate scope, and excellent tolerance.
Structure-activity relationship of antileishmanials neolignan analogues
Aveniente, Mario,Pinto, Eduardo F.,Santos, Lourivaldo S.,Rossi-Bergmann, Bartira,Barata, Lauro E.S.
, p. 7337 - 7343 (2008/04/05)
Twenty-two synthetic analogues of neolignans comprising β-ketoethers and β-ketosulfides were obtained from condensation reactions among β-bromoketones and phenols or thiophenols, respectively, in basic solutions, and assayed in vitro for activity against
A new synthesis of 2-sulfanyl allylic alcohols and α-sulfanyl ketones from carbonyl compounds and 1-chloroalkyl p-tolyl sulfoxides with carbon-carbon bond-formation
Satoh, Tsuyoshi,Takahashi, Yoshinori,Shirai, Yuuichi,Yamada, Yukie
, p. 1734 - 1738 (2007/10/03)
Reaction of lithium α-sulfinyl carbanions of 1-chloroalkyl p-tolyl sulfoxides with ketones or aldehydes at low temperature gave adducts in almost quantitative yields. Treatment of the adducts derived from ketones with trifluoroacetic anhydride (TFAA) in t
Synthesis and Reactions of Sulfenic Trifluoromethanesulfonic Anhydrides
Effenberger, Franz,Russ, Werner
, p. 3719 - 3736 (2007/10/02)
Sulfenyl halogenides 1 and 4 react with silver trifluoromethanesulfonate (2) to give aryl 3 and alkylsulfenic trifluoromethanesulfonic anhydrides 5, resp., in good yields; 3 and 5 could not be isolated because of their instability. 1H NMR spectroscopic data of 5a, b, each in dichloromethane and nitromethane, resp., are indicative of a dissoziation to adducts of alkylsulfenylium ions and the solvent.Whereas 3 do not react with aromatic compounds, addition products with diphenylacetylene, arylsulfenylvinyl trifluoromethanesulfonates 11, are formed smoothly, which under the reaction conditions immediately cyclize to give benzothiophenes 10 in excellent yields.
