84228-57-9Relevant academic research and scientific papers
Asymmetric amino acid synthesis: Mitsunobu reaction on chiral cyanohydrins
Decicco, Carl P.,Grover, Paul
, p. 529 - 530 (1997)
BOC(SES)NH was reacted with chiral cyanohydrins using the Mitsunobu reaction to give good yields of protected α-aminonitriles, which were converted to chiral amino and imino acids.
Resolution of DL-racemic mixtures
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Page column 6, (2008/06/13)
The present invention relates to a process for the resolution of DL-racemic mixtures of compounds which crystalize in the form of a conglumerate. Both, the D and L-enantiomers are obtained according to the invention in a industrially feasable process by adding chiral enantioselective polymers to the supersaturated solution of the racemat to inhibit crystalization of one enantiomer. Next a DL-racemic mixture of said compound is suspended in about twice the amount of the crystallized enantiomer. Consequently, the opposite enantiomer could be recovered by said suspension by physical separation.
