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Usage

Uses

Used in Pharmaceutical Industry:
L-2-Aminodecanoic acid (S-form) is used as a precursor in drug development for its potential to contribute to the manufacturing of specific pharmaceuticals and bioactive compounds. Its unique properties make it a valuable component in the creation of new medications.
Used in Cosmetics Industry:
In the cosmetics industry, L-2-Aminodecanoic acid (S-form) is utilized as an ingredient for its beneficial properties in formulations, potentially enhancing the effectiveness of cosmetic products.
Used in Food Additives Industry:
L-2-Aminodecanoic acid (S-form) is employed as a component in food additives, leveraging its solubility and reactivity to improve the characteristics of food products.
Used in Biochemical Research:
L-2-Aminodecanoic acid(S-form) serves as a building block in biochemical research, providing a foundation for the synthesis of other compounds and contributing to the advancement of scientific understanding in the field.
Overall, L-2-Aminodecanoic acid (S-form) is a multifaceted chemical with applications that span across different sectors, highlighting its importance in both research and commercial product development.

Upstream product

• 333-60-8 2-oxodecanoic acid 
• 3060-50-2 2,2-diphenylglycine 

Downstream Products

• 70267-29-7 (S)-2-Hydroxydecanoic acid 
• 70267-24-2 (R)-2-hydroxydecanoic acid 
• 117560-23-3 benzyl (2S)-2-aminodecanoate 
• 89371-45-9 (S)-2-((S)-1-Carboxy-ethylamino)-decanoic acid benzyl ester 
• 89371-52-8 (4S)-1-benzyl-3-<(2S)-2-amino>propionyl>-2-oxoimidazolidine-4-carboxylic acid 
• 89371-49-3 (S)-1-Benzyl-3-[(S)-2-((S)-1-ethoxycarbonyl-nonylamino)-propionyl]-2-oxo-imidazolidine-4-carboxylic acid 
• 89371-40-4 benzyl (4S)-1-methyl-3-{(2S)-2-[N-((1S)-1-ethoxycarbonyl-n-nonyl)amino]propionyl}-2-oxo-imidazolidine-4-carboxylate 
• 89371-73-3 tert.-butyl (4S)-1-methyl-3-{(2S)-2-[N-((1S)-1-benzyloxycarbonyl-n-nonyl)amino]-n-butyryl}-2-oxo-imidazolidine-4-carboxylate 
• 89384-27-0 benzyl (4S)-1-benzyl-3-{(2S)-[N-((1S)-1-ethoxycarbonyl-n-nonyl)amino]propionyl}-2-oxo-imidazolidine-4-carboxylate 
• 89384-28-1 benzyl (4S)-1-benzyl-3-{(2S)-2-[N-((1S)-1-benzyloxycarbonyl-n-nonyl)amino]propionyl}-2-oxo-imidazolidine-4-carboxylate 
• 117560-13-1 (S)-2-((S)-1-Benzyloxycarbonyl-ethylamino)-decanoic acid ethyl ester; compound with (Z)-but-2-enedioic acid 
• 117560-12-0 (S)-2-((S)-1-tert-Butoxycarbonyl-ethylamino)-decanoic acid benzyl ester; compound with (Z)-but-2-enedioic acid 
• 89371-90-4 (S)-2-((S)-1-Benzyloxycarbonyl-ethylamino)-decanoic acid ethyl ester 
• 117560-11-9 (S)-2-((S)-1-tert-Butoxycarbonyl-ethylamino)-decanoic acid benzyl ester 

Relevant academic research and scientific papers

Asymmetric synthesis of (S)-α-(octyl)glycine via alkylation of Ni(II) complex of chiral glycine Schiff base

Over last decade, the use of Ni(II) complexes, derived from of glycine Schiff bases with chiral tridentate ligands, has emerge as a leading methodology for preparation of structurally diverse Tailor-Made Amino Acids, the key structural units in modern medicinal chemistry, and drug design. Here, we report asymmetric synthesis of derivatives of (S)-α-(octyl)glycine ((S)-2-aminodecanoic acid) and its N-Fmoc derivative via alkylation of chiral nucleophilic glycine equivalent with n-octyl bromide. Under the optimized conditions, the alkylation proceeds with excellent yield (98.1%) and diastereoselectivity (98.8% de). The observed stereochemical outcome and convenient reaction conditions bode well for application of this method for large-scale asymmetric synthesis of (S)-2-aminodecanoic acid and its derivatives.

A new type of chiral-pyridoxamines for catalytic asymmetric transamination of α-keto acids

A new type of chiral pyridoxamines bearing an adjacent chiral stereocenter has been developed via multi-step synthesis. The pyridoxamines displayed catalytic activity in asymmetric transamination of α-keto acids to give a variety of optically active amino acids in 27–78% yields with 34–62% ee's under very mild conditions. This work provides a synthetic strategy to construct new chiral pyridoxamines using bromopyridine 7 as a key synthon and also represents an early example of the applications of chiral pyridoxamines in asymmetric catalysis.