84302-12-5

Upstream product

• 84302-19-2 (1R,4R)-1,4-Diphenyl-2,3,7-trioxa-bicyclo[2.2.1]hept-5-ene-5-carboxylic acid methyl ester 
• 1595-64-8 1,5-diphenyl-penta-2,4-diyn-1-ol 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 67-56-1 methanol 
• 1574-79-4 1,5-diphenyl-2,4-pentadiyn-1-one 
• 85574-02-3 (E)-2-Benzoyl-4-oxo-4-phenyl-but-2-enoic acid methyl ester 
• 84302-19-2 1,4-Diphenyl-2,3,7-trioxa-bicyclo[2.2.1]hept-5-ene-5-carboxylic acid methyl ester 
• 4242-46-0 1-cyanobenzyl benzoate 
• 115852-13-6 methyl 2-methoxy-5-phenyl-furan-3-carboxylate 
• 90904-37-3 methyl α,β-dibenzoyl-propionate 

Downstream Products

• 85574-02-3 (E)-2-Benzoyl-4-oxo-4-phenyl-but-2-enoic acid methyl ester 
• 90043-46-2 (3R,3aR,6aS)-2-Oxo-5,6a-diphenyl-2,3,3a,6a-tetrahydro-furo[2,3-b]furan-3,4-dicarboxylic acid dimethyl ester 
• 84302-13-6 Benzoic acid (Z)-1-methoxycarbonyl-3-oxo-3-phenyl-propenyl ester 
• 84302-19-2 (1R,4R)-1,4-Diphenyl-2,3,7-trioxa-bicyclo[2.2.1]hept-5-ene-5-carboxylic acid methyl ester 
• 84302-19-2 1,4-Diphenyl-2,3,7-trioxa-bicyclo[2.2.1]hept-5-ene-5-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Gold-Catalyzed Oxidative Cyclization Involving Nucleophilic Attack to the Keto Group of α,α′-Dioxo Gold Carbene and 1,2-Alkynyl Migration: Synthesis of Furan-3-carboxylates

A multicomponent strategy for the synthesis of functionalized furan-3-carboxylates based on gold-catalyzed oxidative cyclization of diynones with alcohols or water has been developed. Mechanistic studies revealed that a rare nucleophilic attack to the carbonyl group of the α,α′-dioxo gold carbene instead of the carbene center and 1,2-alkynyl group migration were involved in this transformation. This method offers several advantages such as mild conditions, high regio- and chemoselectivity, and wide functional group compatibility.

The first nucleophilic aromatic substitution of suitably activated 2-methoxyfurans with Grignard reagents

The reaction of 2-methoxyfuroates 1 with Grignard reagents 2 leads to tertiary alcohols or SNAr products depending on the position of the alkoxycarbonyl group. OMe-Displacement occurs only for 3-substituted derivatives. It takes place even for 3-acetyl-2-methoxyfuran while the presence of a further ester function at 4 position induces the formation of the sole 4-tertiary alcohol. The OMe-substitution has been verified for a wide range of furans and Grignard reagents and low yields have been found only in the reactions with the benzylic and allylic reagents which are delocalized anions. A mechanistic interpretation is given.

Synthesis of 1,4-diketones by Michael addition of O-aroylmandelonitriles involving rearrangement of aroyl group and decyanation

The anions derived from O-aroylmandelonitriles 1 reacted with Michael addition acceptors such as acrylonitrile (7) and methyl acrylate (10) to give the corresponding 1,4-diketones 12, 13, and 15 in moderate to good yields. Under acidic conditions, the 1,4

Photosensitized Oxidation of Furans. Part 7. Solvent Effects in Thermal Conversion of the endo-Peroxides of Arylfurans

Thermal conversion of the endo-peroxides of the arylfurans (1) in a polar aprotic solvent leads to aroylenol esters (4) and diaroyl epoxides (3), the predominance of one over being concentration dependent.The results can be rationalized on the basis of th