84308-48-5Relevant academic research and scientific papers
SYNTHESE DE DIENES-1,4 FONCTIONNALISES PAR ADDITION DE ZINCIQUES ALLYLIQUES FONCTIONNALISES SUR DES ALCYNES VRAIS ET LEUR CYCLISATION EN HETEROCYCLES OU CARBOCYCLES
Knochel, P.,Normant, J. F.
, p. 1 - 24 (2007/10/02)
The regiospecific addition of functionalized allylic bromides to terminal alkynes in the presence of zinc furnishes a great variety of highly functionalized 1,4-dienes with moderate to good yields.The synthetic utility of these 1,4-dienes is demonstrated by various cyclization reactions leading to an α-methylene-γ-butyrolactone, to 3,5-difunctionalized piperidines, to a cyclic triester and to 6- or 7-membered phosphorus heterocyclic compounds.
"&α-METHYLENE-&γ-PHOSTONES" (5,5-DI- AND 5-MONOALKYL-2-METHOXY-3-METHYLENE-1,2-OXAPHOSPHOLAN-2-ONES). A PHOSPHORUS ANALOG OF THE ONE-STEP REFORMATSKY SYNTHESIS OF &α-METHYLENE-&γ-BUTYROLACTONES FROM KETONES AND ALDEHYDES
Collard, Jean-Noel,Benezra, Claude
, p. 3725 - 3728 (2007/10/02)
The first synthesis of "α-methylene-γ-phostones" (propylphostonates) using dimethyl bromo-3-propen-2 ylphosphonate and ketones and aldehydes, in the presence of zinc, is described.
