84313-94-0

Usage

InChI:InChI=1/C10H8F2O3/c11-7-2-1-6(5-8(7)12)9(13)3-4-10(14)15/h1-2,5H,3-4H2,(H,14,15)

Upstream product

• 108-30-5 succinic acid anhydride 
• 367-11-3 ortho-difluorobenzene 
• 348-61-8 1-bromo-3,4-difluorobenzene 

Downstream Products

• 889656-16-0 4-(3,4-difluorophenyl)pent-4-enoic acid 
• 1006614-50-1 trans-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid 
• 1247668-00-3 methyl 4-(3,4-difluorophenyl)-4-hydroxybutanoate 
• 1006614-50-1 (±)-trans-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid 
• 1450897-24-1 isopropyl 4-(3,4-difluorophenyl)-4-hydroxybutanoate 
• 1267369-02-7 isopropyl 4-(3,4-difluorophenyl)-4-oxobutanoate 
• 1248202-12-1 4-keto-4-(3,4-difluorophenyl)butyric acid methyl ester 
• 84313-93-9 6-[3-fluoro-4-(morpholin-4-yl)phenyl]-4,5-dihydropyridazin-3(2H)-one 
• 889656-07-9 [3-(3,4-difluorophenyl)but-3-enyl]methylamine 
• 889656-17-1 4-(3,4-difluorophenyl)pent-4-en-1-ol 
• 889656-18-2 4-(3,4-difluorophenyl)pent-4-enal 

Relevant academic research and scientific papers

6-PHENYL-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE DERIVATIVES AS PDE3A AND PDE3B INHIBITORS FOR TREATING CANCER

The present invention provides 6-phenyl-4,5-dihydropyridazin-3(2H)- one derivatives of formula (I) : The present invention provides 6-phenyl-4,5-dihydropyridazin-3(2H)- one derivatives of formula (I) :

NOVEL PYRIDAZONES AND TRIAZINONES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The invention provides novel compounds having the general formula wherein R1, R2, R3, X and a are as described in the description and in the claims, as well as or pharmaceutically acceptable salts thereof. The invention also contains compositions including the compounds and methods of using the compounds.

Synthesis of 2-(3,4-difluorophenyl)cyclopropanecarboxylic acid

The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

SYNTHESIS OF 2-(3,4-DIFLUOROPHENYL)CYCLOPROPANECARBOXYLIC ACID

The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity

4-phenyl-4-oxo-butanoic acid derivatives for use in the treatment of the human or animal body by therepy; particularly as kynurenine-3-hydroxylase inhibitors, in the prevention and/or treatment of a neurodegenerative disease wherein the inhibition of such an enyzme is needed. The present invention further comprises a selected class of the above mentioned 4-phenyl-4-oxo-butanoic acid derivatives, their pharmaceutically acceptable salts, a process for their preparation and pharmaceutical compositions containing them.