84319-81-3

Basic information

• Product Name: (1R,5S,7R)-3-butyl-6,7-bis(2-hydroxyphenyl)-3-azabicyclo[3.2.0]heptane-2,4-dione
• CAS NO: 84319-81-3
• Molecular Formula: C₂₂H₂₃NO₄
• Molecular Weight: 365.4223
• Mol File: 84319-81-3.mol

Chemical Properties

• Boiling Point: 482.6°C at 760 mmHg
• Flash Point: 245.7°C
• Density: 1.281g/cm³
• Vapor Pressure: 6.15E-10mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: (1R,5S,7R)-3-butyl-6,7-bis(2-hydroxyphenyl)-3-azabicyclo[3.2.0]heptane-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,5S,7R)-3-butyl-6,7-bis(2-hydroxyphenyl)-3-azabicyclo[3.2.0]heptane-2,4-dione(84319-81-3)
• EPA Substance Registry System: (1R,5S,7R)-3-butyl-6,7-bis(2-hydroxyphenyl)-3-azabicyclo[3.2.0]heptane-2,4-dione(84319-81-3)

Safety Data

• Hazardous Substances Data: 84319-81-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(1R,5S,7R)-3-butyl-6,7-bis(2-hydroxyphenyl)-3-azabicyclo[3.2.0]heptane-2,4-dione is used as a pharmaceutical compound for its potential antioxidant or phenolic properties, which may contribute to the development of new drugs targeting various health conditions.
Used in Chemical Research:
In the field of chemical research, (1R,5S,7R)-3-butyl-6,7-bis(2-hydroxyphenyl)-3-azabicyclo[3.2.0]heptane-2,4-dione serves as a subject for studying its unique reactivity and the effects of its complex structure on chemical behavior.
Used in Material Science:
(1R,5S,7R)-3-butyl-6,7-bis(2-hydroxyphenyl)-3-azabicyclo[3.2.0]heptane-2,4-dione is utilized in material science for exploring its potential applications in the development of new materials, possibly due to its unique structural features and reactivity.

Upstream product

• 84319-80-2 N,N'-dibutyl-c-3,c-4-bis(2-hydroxyphenyl)-r-1,c-2-cyclobutanedicarboxamide 
• 109-73-9 N-butylamine 
• 5248-11-3 (α6aH,α6bH,α12bH,α12cH)-cyclobuta<1,2-c,4-3-c¹>bis<1>benzopyran-6,7-dione 

Downstream Products

• 2973-09-3 n-butylmaleimide 
• 18221-50-6 dihydroxy-stilbene 
• 91-64-5 coumarin 
• 5248-11-3 (α6aH,α6bH,α12bH,α12cH)-cyclobuta<1,2-c,4-3-c¹>bis<1>benzopyran-6,7-dione 

Relevant articles and documents

Thermal Behavior of Head-to-head Coumarin Dimers and Their Lactone-opened Derivatives

The thermal behavior of head-to-head coumarin dimers and twelwe lactone-opened derivatives was investigated.Though the lactone rings in coumarin dimers are very susceptible to nucleophilic ring-opening, heating these derivatives reformed six-membered lactone rings except for certain imide and diamide derivatives.The large neiboring group effect allowed the relactonization by the attack of hydroxyphenyl group to carbonyl carbon in preference to the scission of cyclobutane ring.

REACTION OF SYN HEAD-TO-HEAD COUMARIN DIMER WITH AMINES AND THERMAL BEHAVIOR OF THE ADDUCTS

The lacton-opening reaction of syn head-to-head coumarin dimer with amines gave c-3,c-4-bis(2-hydroxyphenyl)-r-1,c-2-cyclobutanedicarboxamides and/or -dicarboximides.The product ratio of the amide to the imide varied with the reaction temperature and the amount of amine used.Thermal reaction of these lactone-opened derivatives proceeded in two ways depending on the nature of amine moiety to give either the original coumarin dimer or 2,2'-dihydroxystilbene and the maleimide derivative.