84325-98-4

Upstream product

• 20051-06-3 p-Methoxycarbonylmethyl acetophenone 

Downstream Products

• 84326-02-3 [4-(2-Oxo-2H-benzo[1,4]oxazin-3-yl)-phenyl]-acetic acid methyl ester 
• 84326-04-5 [4-(6-Methyl-2-oxo-2H-benzo[1,4]oxazin-3-yl)-phenyl]-acetic acid methyl ester 
• 84326-07-8 Methyl 4-(6,8-dimethyl-2H-1,4-benzoxazin-2-one-3-yl) phenyl acetate 
• 84326-03-4 [4-(6-Chloro-2-oxo-2H-benzo[1,4]oxazin-3-yl)-phenyl]-acetic acid methyl ester 
• 84326-06-7 [4-(8-Chloro-2-oxo-2H-benzo[1,4]oxazin-3-yl)-phenyl]-acetic acid methyl ester 
• 84326-05-6 [4-(6-Nitro-2-oxo-2H-benzo[1,4]oxazin-3-yl)-phenyl]-acetic acid methyl ester 
• 84326-00-1 Ethyl p-methoxycarbonylmethylphenylglyoxylate 

Relevant academic research and scientific papers

Piperazine derivatives, medicaments comprising these compounds, their use and processes for their preparation

The present invention relates to piperazine derivatives of the general formula STR1 in which Ra, Y1 to Y3 and E are defined herein, tautomers thereof, stereoisomers thereof, including their mixtures, and salts thereof, and in particular physiologically tolerated salts thereof with inorganic or organic acids or bases. These compounds have valuable pharmacological properties, such as aggregation-inhibiting activity. This invention also relates to medicaments comprising these compounds and to processes for the preparation of these compounds.

Antiinflammatory Agents: Part VI - Synthesis and Antiinflammatory Activity of Some New 4-(6,8-Substituted-2H-1,4-Benzoxazin-2-one-3-yl)phenylalkanoic Acid Esters

A number of methyl 4-(6,8-substituted-2H-1,4-benzoxazin-2-one-3-yl)phenylacetates (V, 1-6) and the corresponding α-methylacetates (V, 7-12) have been synthesized and evaluated for their antiinflammatory activity against carrageenan-induced oedema in rats.