84392-25-6

Basic information

• Product Name: 4'-ISOPROPYLBIPHENYL-2-CARBOXYLIC ACID
• Synonyms: 4'-ISOPROPYLBIPHENYL-2-CARBOXYLIC ACID
• CAS NO: 84392-25-6
• Molecular Formula: C₁₆H₁₆O₂
• Molecular Weight: 240.3
• Mol File: 84392-25-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4'-ISOPROPYLBIPHENYL-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-ISOPROPYLBIPHENYL-2-CARBOXYLIC ACID(84392-25-6)
• EPA Substance Registry System: 4'-ISOPROPYLBIPHENYL-2-CARBOXYLIC ACID(84392-25-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 84392-25-6(Hazardous Substances Data)

Usage

General Description

4'-Isopropylbiphenyl-2-carboxylic acid is a chemical compound with the molecular formula C15H14O2. It belongs to the class of biphenyl carboxylic acids and is commonly used in organic synthesis and pharmaceutical research. 4'-ISOPROPYLBIPHENYL-2-CARBOXYLIC ACID is a white to off-white crystalline powder that is sparingly soluble in water, but soluble in organic solvents. It is known to have potential applications in drug design and development due to its ability to act as a ligand for various biological targets. Additionally, its chemical structure and properties make it suitable for use as a building block in the synthesis of more complex organic compounds.

Upstream product

• 653589-95-8 2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzoic acid methyl ester 
• 17356-09-1 4-iodocumene 
• 65-85-0 benzoic acid 
• 682339-49-7 4'-isopropylbiphenyl-2-carboxaldehyde 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 586-61-8 4-iso-propylbromobenzene 
• 400727-79-9 ethyl 4'-isopropylbiphenyl-2-carboxylate 

Downstream Products

• 682340-41-6 4'-isopropylbiphenyl-2-carboxylic acid (3-methoxymethyl-2,3-dihydrobenzo[1,4]dioxin-6-yl)amide 
• 121794-40-9 2-bromo-3-methylbenzoic acid chloride 

Relevant articles and documents

SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS

The application relates to substituted hydantoinamides of formula (I) as ADAMTS7 antagonists, to processes for their preparation, their use alone or in combination for the treatment or prophylaxis of diseases, in particular of cardiovascular diseases, including atherosclerosis, coronary artery disease (CAD), peripheral vascular disease (PAD), arterial occlusive disease or restenosis after angioplasty. R1 is hydrogen, alkyl, cycloalkyl, heterocycloalkyl, heteroaryl or phenyl; R2 is hydrogen, cyano, halogen, alkylsulfonyl, alkyl, cycloalkyl or alkoxy; R3, R4, R5, R6, R7 and R8 are independently hydrogen, halogen, alkyl or alkoxy; most groups being optionally substituted; with the proviso that at least one of R2, R3, R4 is H; X1, X2, X3, X4, X5 and X6 are independently N or C; with the proviso that in each ring maximal one X is N.

GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS

Compounds represented by formula (I): are inhibitors of gut microsomal triglyceride transfer protein. Such compounds are useful in treating diseases or conditions such as diabetes and obesity, along with patients are risk for developing such diseases or conditions.

Nonpeptide arginine vasopressin antagonists for both V(1A) and V2 receptors: Synthesis and pharmacological properties of 2-Phenyl-4'- [(2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]benzanilide derivatives

A series of compounds structurally related to 4'-[(2,3,4,5-tetrahydro- 1H-1-benzazepin-1-yl)carbonyl]benzanilide was synthesized and demonstrated to have arginine vasopressin (AVP) antagonist activity for both V(1A) and V2 receptors. The introduction of a phenyl or a 4-substituted phenyl group into the ortho position of the benzoyl moiety resulted in an increase in both binding affinity and antagonistic activity. The 2-(4-methylphenyl) derivative (1g) exhibited high antagonistic activities for both V(1A) (8.6- fold) and V2 (38-fold) receptors and high oral activity (8.6-fold) compared with the 2-methyl lead compound (1a). Detail of the synthesis and the pharmacological properties of this series are presented.