84393-97-5Relevant academic research and scientific papers
Flash Vacuum Pyrolysis of Stabilised Phosphorus Ylides. Part 1. Preparation of Aliphatic and Therminal Alkynes
Aitken, R. Alan,Atherton, J. Ian
, p. 1281 - 1284 (2007/10/02)
Thermal extrusion of Ph3PO from β-oxoalkylidenetriphenylphosphoranes 4 to give the alkynes 5, which under conventional pyrolysis conditions is restricted to cases in which R1 is an electron withdrawing group, has been successfully achieved for R1=H or alkyl by using FVP.The method allows convenient construction of multigram quantities of the alkynes 5 from alkyl halides 1 and allows convenient construction of multigram quantities of the alkynes 5 from alkyl halides 1 and acid chlorides 3 in three steps with good overall yields.Under the conditions used the ylides with R2 = cyclobutyl also undergo less of ethene to provide convenient access to the vinylalkynes 6.
Reactions with Phosphine Alkylenes, XLII. A Sequence for the Preparation of Acetylenes Starting from Carboxylic Chlorides and Phosphorus Ylides via 1,2-Diketones.
Bestmann, Hans Juergen,Kumar, Kamlesh,Kisielowski, Lothar
, p. 2378 - 2382 (2007/10/02)
Phosphorus ylides 1 and carboxylic chlorides 2 react with transylidation to give acyl ylides 3 which are oxidized with the adduct of ozone to triphenyl phosphite to yield 1,2-diketones 5.These are converted into the bis(hydrazones) 6 which are oxidized with O2/CuCl in pyridine giving acetylenes 7.
