84409-26-7Relevant academic research and scientific papers
CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES
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Paragraph 0230; 0235-0236, (2020/03/28)
A chemoselective and reactive Mn(CF3-PDP) catalyst system that enables for the first time the strategic advantages of late-stage aliphatic C—H hydroxylation to be leveraged in aromatic compounds. This discovery will benefit small molecule therapeutics by enabling the rapid diversification of aromatic drugs and natural products and identification of their metabolites.
Chemoselective methylene oxidation in aromatic molecules
Zhao, Jinpeng,Nanjo, Takeshi,de Lucca, Emilio C.,White, M. Christina
, p. 213 - 221 (2019/01/04)
Despite significant progress in the development of site-selective aliphatic C–H oxidations over the past decade, the ability to oxidize strong methylene C–H bonds in the presence of more oxidatively labile aromatic functionalities remains a major unsolved
SYNTHESIS AND PROPERTIES OF 1-ARYL-3-OXO-1-CYCLOPENTANECARBOXYLIC ACIDS AND THEIR DERIVATIVES
Mndzhoyan, Sh.L.,Martirosyan, A.O.,Ovakimyan, A.R.
, p. 1648 - 1651 (2007/10/02)
A synthesis was developed for 1-phenyl- and 1-(alkoxyphenyl)-3-oxo-1-cyclopentanecarboxylic acids, and some of their derivatives were obtained.
