84414-86-8Relevant academic research and scientific papers
CHROMIUM(II) MEDIATED THREO SELECTIVE SYNTHESIS OF HOMOALLYL ALCOHOLS
Hiyama, Tamejiro,Kimura, Keizo,Nozaki, Hitosi
, p. 1037 - 1040 (1981)
Remarkable threo selectivity is observed in the reaction of aldehydes with trans- and cis-1-bromo-2-butene with the aid of chromium(II) salts.Solvent effect as well as the synthetic application is discussed.
Cobalt-Catalyzed Diastereo- And Enantioselective Reductive Allyl Additions to Aldehydes with Allylic Alcohol Derivatives via Allyl Radical Intermediates
Wang, Lei,Wang, Lifan,Li, Mingxia,Chong, Qinglei,Meng, Fanke
, p. 12755 - 12765 (2021/08/30)
Catalytic generation of ambiphilic π-allyl-metal complexes and their utility in enantioselective transformations constitutes a powerful approach for introduction of allyl groups to a molecule. Herein an unprecedented cobalt-catalyzed highly site-, diastereo-, and enantioselective protocol for stereoselective formation of nucleophilic allyl-Co(II) complexes followed by addition to aldehydes is presented. The reaction features diastereo- and enantioconvergent conversion of easily accessible allylic alcohol derivatives to diversified enantioenriched homoallylic alcohols with a remarkably broad scope of allyl groups that can be introduced. Mechanistic studies indicated that allyl radical intermediates were involved in this process. These new discoveries establish a new strategy for development of enantioselective transformations through capture of radicals by chiral Co complexes, pushing forward the frontier of Co complexes for enantioselective catalysis.
Enantioselective syntheses of 1,4-pentadien-3-yl carbinols via br?nsted acid catalysis
Gao, Shang,Chen, Ming
, p. 400 - 404 (2020/01/11)
An asymmetric addition of substituted 1,3-pentadienylboronates to aldehydes via Br?nsted acid catalysis is reported. Under the developed conditions, a variety of synthetically useful 1,4-pentadien-3-yl carbinols were obtained in good yields with high enan
STEREOSELECTIVE ACYCLIC SYNTHESIS VIA ALLYLMETALS: STRUCTURAL DEPENDENCE IN A LEWIS-ACID CATALYZED ADDITION OF ALLYLTINS TO ALDEHYDES
Koreeda, Masato,Tanaka, Yoshio
, p. 1299 - 1302 (2007/10/02)
Lewis-acid catalyzed reaction of allyltins with aldehydes at -78 deg C provide homoallyl alcohols with high stereoselectivity; 2-alkenyltins in general provide erythro adducts preferentially with an erithro/threo ratio greater than 12/1, whereas only thre
