844439-52-7

Basic information

• Product Name: (R)-β-N-acetyl-p-chloro-phenylalanine methyl ester
• Synonyms: (R)-β-N-acetyl-p-chloro-phenylalanine methyl ester;(betaR)-beta-(Acetylamino)-4-chlorobenzenepropanoic acid ethyl ester
• CAS NO: 844439-52-7
• Molecular Formula: C13H16ClNO3
• Molecular Weight: 269.72404
• Mol File: 844439-52-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.188
• CAS DataBase Reference: (R)-β-N-acetyl-p-chloro-phenylalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-β-N-acetyl-p-chloro-phenylalanine methyl ester(844439-52-7)
• EPA Substance Registry System: (R)-β-N-acetyl-p-chloro-phenylalanine methyl ester(844439-52-7)

Safety Data

• Hazardous Substances Data: 844439-52-7(Hazardous Substances Data)

Usage

General Description

(R)-β-N-acetyl-p-chloro-phenylalanine methyl ester is a chemical compound that is a derivative of the amino acid phenylalanine. It is an enantiomer of the compound β-N-acetyl-p-chloro-phenylalanine methyl ester, meaning it has a specific three-dimensional arrangement of atoms that gives it different properties and interactions. (R)-β-N-acetyl-p-chloro-phenylalanine methyl ester is often used in research and studies related to amino acid metabolism, enzyme kinetics, and pharmaceutical development. It may have potential applications in the treatment of various neurological and psychiatric disorders, as well as in the development of new drugs targeting specific molecular pathways. However, further research is needed to fully understand the potential uses and effects of this compound.

Upstream product

• 434957-51-4 ethyl 3-acetamido-3-(4-chlorophenyl)-2-propenoate 

Relevant articles and documents

Chiral 1-phenylethylamine-derived phosphine-phosphoramidite ligands for highly enantioselective Rh-catalyzed hydrogenation of β-(acylamino) acrylates: Significant effect of substituents on 3,3′-positions of binaphthyl moiety

A series of new chiral phosphine-phosphoramidite ligands with a 3,3′-substituted binaphthyl moiety were prepared from 1-phenylethylamine, and successfully applied in the Rh-catalyzed asymmetric hydrogenation of β-(acylamino)acrylates. The research disclosed that the substituents on the 3,3′-positions of binaphthyl moiety significantly influenced the enantioselectivity.

Highly effective chiral ortho-substituted BINAPO ligands (o-BINAPO): Applications in Ru-catalyzed asymmetric hydrogenations of β-aryl-substituted β-(acylamino)acrylates and β-keto esters

A novel family of chiral ortho-substituted BINAPO ligands (o-BINAPO) were synthesized from BINOL, and their Ru complexes were highly efficient catalysts for asymmetric hydrogenation of β-aryl-substituted β-(acylamino)acrylates and β-aryl-substituted β-keto esters. The Ru-bisphosphinite catalysts can tolerate an E/Z mixture of β-aryl-substituted β-(acylamino)acrylates. These highly enantioselective hydrogenations provide a useful way to prepare β-aryl-substituted β-amino acids and β-hydroxyl acids. Copyright