84445-76-1 Usage
Structure
A chemical compound containing a benzene ring with a five-membered imidazole ring attached to it, an acetyl group (-COCH3) and a methyl group (-CH3) attached to the benzene ring.
Properties
1H-Benzimidazole,1-acetyl-5-methyl-(9CI) is a derivative of benzimidazole, which has shown a wide range of biological activities, including antiviral, antifungal, and anticancer properties. The acetylation and methylation of the benzimidazole ring may alter its pharmacological profile.
Applications
Potential applications in pharmaceutical and medicinal chemistry, as a candidate for drug development and research purposes.
Safety
Should be handled and used with caution, following appropriate safety protocols and guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 84445-76-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,4,4 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 84445-76:
(7*8)+(6*4)+(5*4)+(4*4)+(3*5)+(2*7)+(1*6)=151
151 % 10 = 1
So 84445-76-1 is a valid CAS Registry Number.
84445-76-1Relevant articles and documents
Synthesis of N-Acetylbenzimidazole Derivatives
Tanaka, Kenjiro,Shimazaki, Michiko,Murakami, Yasuoki
, p. 2714 - 2722 (2007/10/02)
For the structure determination of thiazolobenzimidazol-3(2H)-one derivatives (2 or 3) they were converted to the corresponding 1-acetylbenzimidazoles (4) by desulfurization.The latter compounds (4) were alternatively prepared by the cyclization of 2-aminoacetanilide derivatives (5) with CS2 in dimethylformamide (DMF), followed by desulfurization with Raney Ni.However, the reactions of 5 with ethyl orthoformate/H2SO4 in DMF gave a mixture of 4 and its acetyl-rearranged product (7).Keywords-acetyl group; rearrangement; thiazolobenzimidazol-3(2H)-one; N-acetylbenzimidazoles; ethyl orthoformate; carbon disulfide; desulfurization
