53476-34-9

Basic information

• Product Name: 4-ACETAMIDO-3-AMINOTOLUENE
• Synonyms: N1-(2-AMINO-4-METHYLPHENYL)ACETAMIDE;4-ACETAMIDO-3-AMINOTOLUENE;acetamide, N-(2-amino-4-methylphenyl)-;N-(2-amino-4-methylphenyl)acetamide(SALTDATA: FREE);N-(2-amino-4-methyl-phenyl)ethanamide
• CAS NO: 53476-34-9
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.2
• Mol File: 53476-34-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 357.5°Cat760mmHg
• Flash Point: 170°C
• Appearance: /
• Density: 1.163g/cm³
• Vapor Pressure: 2.71E-05mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 4-ACETAMIDO-3-AMINOTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ACETAMIDO-3-AMINOTOLUENE(53476-34-9)
• EPA Substance Registry System: 4-ACETAMIDO-3-AMINOTOLUENE(53476-34-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 53476-34-9(Hazardous Substances Data)

Usage

General Description

4-Acetamido-3-aminotoluene, also known as 4-Acetamido-m-toluidine, is a chemical compound commonly used in the production of dyes. It is a white to light brown crystalline powder with a molecular formula of C9H12N2O and a molecular weight of 164.21 g/mol. 4-ACETAMIDO-3-AMINOTOLUENE is often used as an intermediate in the synthesis of azo dyes, which are widely used in the textile and printing industries. 4-Acetamido-3-aminotoluene is also used as a dye precursor in hair dyes and color cosmetics. However, it is important to note that this chemical is classified as a possible human carcinogen, and its use and handling should be carefully regulated to minimize potential health risks.

InChI:InChI=1/C9H12N2O/c1-6-3-4-9(8(10)5-6)11-7(2)12/h3-5H,10H2,1-2H3,(H,11,12)

Upstream product

• 89-62-3 4-methyl-2-nitroaniline 
• 612-45-3 4-methyl-2-nitroacetanilide 
• 64-19-7 acetic acid 

Downstream Products

• 132841-43-1 N-[2-(3-Allyl-thioureido)-4-methyl-phenyl]-acetamide 
• 1514589-87-7 N-(4-methyl-2-{[(5-methylfuran-2-yl)methylidene]amino}phenyl)acetamide 
• 1514590-13-6 C₂₁H₂₀FN₃ 
• 1514590-11-4 C₂₂H₂₃N₃O 
• 1514589-92-4 C₁₅H₁₈N₂O₂ 
• 120209-26-9 2,5-Dimethyl-6-nitrobenzimidazole 
• 2963-65-7 5-methyl-2-phenyl-1H-1,3-benzimidazole 
• 27231-36-3 2-mercapto-5-methylbenzimidazole 
• 84445-76-1 1-(5-Methyl-benzoimidazol-1-yl)-ethanone 
• 113001-05-1 N-(4-Methyl-2-{[1-(2-nitro-phenyl)-meth-(Z)-ylidene]-amino}-phenyl)-acetamide 
• 84445-82-9 1-acetyl-6-methylbenzimidazole 
• 132841-39-5 N-[4-Methyl-2-(3-phenyl-thioureido)-phenyl]-acetamide 
• 21541-33-3 1-acetyl-5-methyl-1H-benzimidazole-2-thiol 
• 27231-36-3 5-methyl-1H-benzoimidazole-2-thiol 

Relevant articles and documents

Synthesis of 2-methyl-1-[(5-methylfuran-2-yl)methyl]- and 2-methyl-1-[(5-methylpyrrol-2-yl)methyl]-1H-benzimidazoles

A method for the synthesis of 2-methyl-1-[(5-methylfuran-2-yl)methyl]-1H- benzimidazoles based on the intramolecular cyclization of vicinal N-[(5-methylfuran-2-yl)methyl]aminoanilides has been developed. A study was carried out on the protolytic opening o

o-Nitrobenzylidene Compounds. Part 4. The Cyanide-induced Cyclisation of o-Acetamido-N-(o-nitrobenzylidene)anilines: an Improved Route to Quinoxalinocinnolines

Cyclisation of o-acetamido-N-(o-nitrobenzylidene)anilines (7) with potassium cyanide in methanol (preferably under nitrogen) leads in most cases to quinoxalinocinnolines (6) of unambiguous substitution pattern.In some cases, cyclisation appears to be incomplete, and 2-amino-3-(o-nitrophenyl)quinoxalines (11) are obtained as by-products; in certain cases quinoxalinocinnoline 5-oxides (10) are also detected.These by-products are assumed to result from oxidation of intermediates in the cyclisation process (7) ----> (6).