844494-24-2

Upstream product

• 67760-85-4 (S)-2-methyl-5-hexen-3-ol 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 844494-27-5 (4R,2E)-4-(p-methoxybenzyloxy)-5-methylhex-2-enyl acetate 
• 189164-67-8 (4R,2E)-4-(p-methoxybenzyloxy)-5-methylhex-2-en-1-ol 
• 929568-32-1 (3S)-3-(4-methoxybenzyloxy)-4-methyl-pentanal 
• 929568-38-7 (3S,5E,7R,8R,9S)-9-[(3R,4S)-3-(4-methoxybenzyloxy)-4-methyl-hex-5-enoyloxy]-3-(4-methoxybenzyloxy)-2,6,8-trimethylundeca-5,10-dien-7-ol 
• 929568-43-4 (3S,5E,8S,9S)-9-(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-2,6,8-trimethylundeca-5,10-dien-7-one 
• 929568-37-6 (3S,5E,8S,9S)-9-hydroxy-3-(4-methoxybenzyloxy)-2,6,8-trimethylundeca-5,10-dien-7-one 

Relevant academic research and scientific papers

Hydrocarbon oxidation vs C-C bond-forming approaches for efficient syntheses of oxygenated molecules

(Chemical Equation Presented) A hydrocarbon oxidation approach has been applied to the construction of several linear (E)-allylic alcohols that have served as intermediates in the synthesis of natural products and natural product-like molecules. In the original syntheses, these intermediates were constructed using a standard Wittig-type olefination approach. We report here that routes to these same intermediates designed around a hydrocarbon oxidation approach are more efficient both in the total number of functional group manipulations (FGMs) and overall steps, as well as in the overall yield.

An Evans-Tishchenko-ring-closing metathesis approach to medium-ring lactones

A new approach to the synthesis of medium-ring lactones is reported based on sequential Evans-Tishchenko and ring-closing metathesis (RCM) reactions. High diastereoselectivity (>95:5) is demonstrated in the Evans-Tishchenko reaction of unsaturated aldehyd