84452-29-9Relevant academic research and scientific papers
N-CARBODIIMIDES. ISOMERIC TRANSFORMATIONS AND REACTIONS WITH PROTON-CONTAINING NUCLEOPHILIC REAGENTS
Vovk, M. V.,Dorokhov, V. I.,Samarai, L. I.
, p. 654 - 658 (2007/10/02)
The conditions for the isomerization of N-carbodiimides to N-alkylidene-N'-acylureas were investigated.In the reaction of N-carbodiimides with alcohols, phenols, thiophenols, and imines fragmentation of the carbodiimides occurs with the formation of 1-alkoxy-, 1-aryloxy-, 1-arylthio-, and 1-alkylideneaminoalkyl isocyanates and amides.The products from the reaction with water and with tert-butylamine are the amide, ketone, and N-alkylimine.
N,N'-BIS(1-CHLOROALKYL)CARBODIIMIDES. II. REACTIONS WITH PROTON-CONTAINING NUCLEOPHILIC REAGENTS
Fetyukhin, V. N.,Vovk, M. V.,Pirozhenko, V. V.,Samarai, L. I.
, p. 1822 - 1828 (2007/10/02)
The reactions of N,N'-bis(1-chloroalkyl)carbodiimides with proton-containing nucleophilic reagents were investigated.It was shown that substitution products retaining the carbodiimide structure are formed in the reactions with alcohols and phenols.The action of water or primary amines is accompanied by fragmentation of the molecule and leads to the production of chloroformamidine or N-substituted guanidines.Secondary amines act on N,N'-bis(1-chloroalkyl)carbodiimides to form diazadienes, which exist as mixtures of Z,E isomers.
