84454-05-7

Upstream product

• 16814-08-7 diethyl 1-aminophenylmethylphosphonate 
• 98-59-9 p-toluenesulfonyl chloride 
• 762-04-9 Diethyl phosphonate 
• 51608-60-7 N-(benzylidene)-p-methylbenzenesulfonamide 
• 598-02-7 Diethyl phosphate 
• 51608-60-7 phenyl N-tosyl imine 
• 13716-45-5 diethyl trimethylsilyl phosphite 
• 762-04-9 phosphonic acid diethyl ester 
• 100-52-7 benzaldehyde 

Downstream Products

• 1416426-75-9 (S)-diethyl (cyano(4-methylphenylsulfonamido)(phenyl)methyl)phosphonate 
• 42077-97-4 diethyl (S)-(-)-α-aminobenzylphosphonate 

Relevant academic research and scientific papers

Enantioselective Synthesis of α-Amino Phosphonates via Pd-Catalyzed Asymmetric Hydrogenation

A highly enantioselective palladium-catalyzed hydrogenation of a series of linear and cyclic α-iminophosphonates has been achieved, providing efficient access to optically active α-aminophosphonates with up to 99% ee. (Chemical Equation Presented).

Asymmetric synthesis of functionalized tetrasubstituted α-aminophosphonates through enantioselective aza-Henry reaction of phosphorylated ketimines

Bifunctional Cinchona alkaloid thioureas efficiently catalyze asymmetric nucleophilic addition of nitromethane to ketimines derived from α-aminophosphonic acids to afford tetrasubstituted α-amino-β-nitro-phosphonates. Catalytic hydrogenation of (S)-α-amin

Asymmetric cyanation of a-ketiminophosphonates catalyzed by cinchona alkaloids: Enantioselective synthesis of tetrasubstituted a-aminophosphonic acid derivatives from trisubstituted a-aminophosphonates

An enantioselective synthesis of tetrasubstituted a-phosphono-a-amino nitriles through asymmetric cyanation of a-ketiminophosphonates catalyzed by Cinchona alkaloids is reported. a-Ket- ACHTUNGTRENUNGiminophosphonates are generated, in a very efficient sy

Lanthanide amido complexes incorporating amino-coordinate-lithium bridged bis(indolyl) ligands: Synthesis, characterization, and catalysis for hydrophosphonylation of aldehydes and aldimines

Two series of new lanthanide amido complexes supported by bis(indolyl) ligands with amino-coordinate-lithium as a bridge were synthesized and characterized. The interactions of [(Me3Si)2N] 3LnIII(μ-Cl)Li(THF)su

Iodine-catalyzed efficient hydrophosphonylation of N-tosyl aldimines

(Chemical Equation Presented) Treatment of N-tosyl aldimines with dialkyl trimethylsilyl phosphites at 0°C in the presence of iodine as a catalyst afforded the corresponding sulfonamide phosphonates in excellent yields within 1.5 to 2.5 h.

A facile synthesis of N-sulfonyl and N-sulfinyl aldimines under Barbier-type conditions

(Chemical Equation Presented) A convenient synthesis of N-sulfonyl- and N-sulfinylimines by the condensation of aldehydes with sulfonyl or sulfinyl amides in the presence of benzyl bromide and zinc dust at room temperature under the Barbier-type condition

Organocatalytic enantioselective hydrophosphonylation of sulfonylimines having a heteroarenesulfonyl group as a novel stereocontroller

Organocatalytic enantioselective hydrophosphonylation of imines having the a heteroarenesulfonyl group afforded the respective products with high enantioselectivity. Both enantiomers of α-amino phosphonates were obtained by using different Cinchona alkalo

δ and α SP3 C-H bond oxidation of sulfonamides with PhI(OAc)2/I2 under metal-free conditions

(Chemical Equation Presented) An efficient δ and α sp 3 C-H bond oxidation of sulfonamides with PhI(OAc)2/I 2 under metal-free conditions has been reported. The reaction provides a useful route to pyrrolidines, N-sulfonyli

A Facile Synthesis of O,O-Dialkyl-α-(p-toluenesulphonamido)-benzyl Phosphonates

A series of O,O-dialkyl-α-(p-toluenesulphonamido)benzyl phosphonates have been synthesised by the addition of alkyl phosphites to N-benzylidene-p-toluenesulphonamide.The compounds exhibit chemical shift nonequivalence of prochiral alkoxy groups.Furthermore, on the basis of observed 2JPCH, a preferred conformation with benzylic hydrogen in gauche-disposition to phosphoryl group has been suggested.