84468-52-0

Basic information

• Product Name: 2,3-Dimethyl-piperazine
• Synonyms: 2,3-Dimethylpiperazine, cis + trans, 95%;2,3-DiMethyl-piperazine, 95+%;2,3-Dimethylpiperazine 95%;Piperazine,2,3-dimethyl-
• CAS NO: 84468-52-0
• Molecular Formula: C₆H₁₄N₂
• Molecular Weight: 114.19
• Product Categories: pharmacetical
• Mol File: 84468-52-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 82-88°C
• Appearance: /
• Sensitive: Air Sensitive
• CAS DataBase Reference: 2,3-Dimethyl-piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dimethyl-piperazine(84468-52-0)
• EPA Substance Registry System: 2,3-Dimethyl-piperazine(84468-52-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 84468-52-0(Hazardous Substances Data)

Usage

General Description

2,3-Dimethyl-piperazine is a chemical compound that belongs to the class of piperazine derivatives. It is a clear, colorless liquid with a faint amine-like odor. The compound is primarily used as an intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds. 2,3-Dimethyl-piperazine is also employed as a solvent for various organic reactions and as a corrosion inhibitor in industrial applications. Additionally, it is used in the synthesis of dyes, rubber chemicals, and other specialty chemicals. The compound is considered to be relatively stable under normal conditions, but it should be handled and stored carefully to avoid potential hazards associated with its toxicity and flammability. Overall, 2,3-Dimethyl-piperazine plays a crucial role in the manufacturing and synthesis of a wide range of chemical products.

Upstream product

• 57193-34-7 trans-2,3-dimethylpiperazine 
• 5910-89-4 2,3-dimethylpyrazine 
• 107-15-3 ethylenediamine 
• 15986-92-2 5,6-dimethyl-2,3-dihydropyrazine 

Downstream Products

• 57193-34-7 (+)-trans-2,3-dimethyl-piperazine 
• 57193-34-7 (-)-trans-2,3-dimethyl-piperazine 
• 110150-15-7 (+/-)-2r,3t-dimethyl-1,4-bis-(toluene-4-sulfonyl)-piperazine 
• 5910-89-4 2,3-dimethylpyrazine 
• 1240583-15-6 2,3-dimethylpiperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Novel monoacylglycerol lipase inhibitor as well as preparation method and application thereof

The invention discloses a novel monoacylglycerol lipase inhibitor as well as a preparation method and application thereof. Specifically, the invention provides a compound shown as a formula I, or a pharmaceutically acceptable salt, a stereoisomer, or a deuterated derivative thereof. Experimental results show that the compound provided by the invention can effectively inhibit MAGL activity, can beused for preparing an MAGL inhibitor and preparing medicines for preventing and/or treating diseases (including endometrial cancer, colorectal cancer, liver cancer, breast cancer, ovarian cancer, neurodegenerative diseases and the like) related to abnormal MAGL activity, and has a wide application prospect.

Reduction of Heterocycles with Nickel-Aluminum Alloy

Pyrazines, pyridazines, isoxazoles, oxazole, 4-methylpyrimidine, and indole are reduced by nickel-aluminum alloy in potassium hydroxide solution.The reaction is simple to carry out and does not require special apparatus or hydrogen atmospheres.The products were the fully hydrogenated species although benzene rings were not attacked. 4-Methylpyrimidine gave 1,3-diaminobutane and oxazole gave 2-(methylamino)ethanol.It was found that the reaction frequently exhibited an induction period.