84477-19-0Relevant academic research and scientific papers
Cyclization of 4-Hydroxy-(E)-2-alkenoic Esters: Simple Synthesis of Butenolides
Tanikaga, Rikuhei,Yamashita, Hiroshi,Kaji, Aritsune
, p. 416 - 417 (2007/10/02)
Simple treatment of 4-hydroxy-(E)-2-alkenoic esters with benzenethiol leads to cyclization to give 3-phenylthio-4-alkanolides, which are easily converted into 3-phenylthio-2-alken-4-olides and 2-alken-4-olides (Δα,β-butenolides).
SELECTIVE REACTIONS OF THIOLATE ANIONS WITH 4-HYDROXY-E-2-ALKENOIC ESTERS OR 4-METHANESULFONYLOXY-E-2-ALKENOIC ESTERS. SYNTHESIS OF 2-ALKEN-4-OLIDES (Δα,β-BUTENOLIDES) AND E,E-2,4-ALKADIENOIC ESTERS
Tanikaga, Rikuhei,Nozaki, Yoshihito,Tanaka, Kazuhiko,Kaji, Aritsune
, p. 1703 - 1706 (2007/10/02)
Methyl 4-hydroxy-E-2-alkenoates prepared from aldehydes in one step, undergo the Michael reactions with thiolate anions to give 4-alkanolide derivatives, which are converted into 2-alken-4-olides.Methyl 4-methanesulfonyloxy-E-2-alkenoates undergo the substitution reactions, and subsequent treatments give methyl E,E-2,4-alkadienoates.
