73281-90-0

Basic information

• Product Name: Acetic acid, [(4-chlorophenyl)sulfinyl]-, methyl ester
• CAS NO: 73281-90-0
• Molecular Formula: C9H9ClO3S
• Molecular Weight: 232.688
• Mol File: 73281-90-0.mol

Chemical Properties

• CAS DataBase Reference: Acetic acid, [(4-chlorophenyl)sulfinyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [(4-chlorophenyl)sulfinyl]-, methyl ester(73281-90-0)
• EPA Substance Registry System: Acetic acid, [(4-chlorophenyl)sulfinyl]-, methyl ester(73281-90-0)

Safety Data

• Hazardous Substances Data: 73281-90-0(Hazardous Substances Data)

Upstream product

• 102714-52-3 methyl 2-(p-chlorophenylsulphinyl)-4-methyl-3-piperidinopentanoate 
• 15446-15-8 methyl 2-[(4-chlorophenyl)thio]acetate 
• 106-54-7 p-Chlorothiophenol 
• 102714-51-2 methyl 2-(p-chlorophenylsulphinyl)-3-(2-methylpiperidino)-3-phenylpropanoate 
• 102714-49-8 methyl 2-(p-chlorophenylsulphinyl)-3-phenyl-3-pyrrolidinopropanoate 
• 111220-78-1 methyl 2-(p-chlorophenylsulphinyl)-3-hexanethyleneimino-3-phenylpropanoate 
• 102714-50-1 methyl 2-(p-chlorophenylsulphinyl)-3-phenyl-3-piperidinopropanoate 
• 111220-77-0 methyl 2-(p-chlorophenylsulphinyl)-3-(3-methylpiperidino)-3-phenylpropanoate 
• 111220-81-6 methyl 2-(p-chlorophenylsulphinyl)-4-methyl-3-(4-methylpiperidino)pentanoate 
• 111220-79-2 methyl 2-(p-chlorophenylsulphinyl)-3-(4-methoxyphenyl)-3-piperidinopropanoate 
• 102714-56-7 methyl 2-(p-chlorophenylsulphinyl)-3-(N,N-dimethylamino)-3-phenylpropanoate 

Downstream Products

• 102714-56-7 methyl 2-(p-chlorophenylsulphinyl)-3-(N,N-dimethylamino)-3-phenylpropanoate 
• 102714-50-1 methyl 2-(p-chlorophenylsulphinyl)-3-phenyl-3-piperidinopropanoate 
• 102714-50-1 methyl 2-(p-chlorophenylsulphinyl)-3-phenyl-3-piperidinopropanoate 
• 102714-50-1 methyl 2-(p-chlorophenylsulphinyl)-3-phenyl-3-piperidinopropanoate 
• 84477-18-9 (E)-3-(1-Hydroxy-cyclohex-3-enyl)-acrylic acid methyl ester 
• 111220-80-5 methyl 2-(p-chlorophenylsulphinyl)-4-methyl-3-(2-methylpiperidino)pentanoate 
• 111220-80-5 methyl 2-(p-chlorophenylsulphinyl)-4-methyl-3-(2-methylpiperidino)pentanoate 
• 111220-77-0 methyl 2-(p-chlorophenylsulphinyl)-3-(3-methylpiperidino)-3-phenylpropanoate 
• 111220-77-0 methyl 2-(p-chlorophenylsulphinyl)-3-(3-methylpiperidino)-3-phenylpropanoate 
• 102714-42-1 (E)-methyl 2-(p-chlorophenylsulphinyl)-3-phenylprop-2-enoate 
• 69529-90-4 <(4-Chlorophenyl)sulfinyl>acetic acid 
• 125706-42-5 (S)-(-)-<(4-Chlorophenyl)sulfinyl>acetic acid 
• 102340-69-2 (R)-(+)-Methyl <(4-chlorophenyl)sulfinyl>acetate 
• 111168-10-6 (E)-4-Hydroxy-6-(4-methoxy-phenyl)-hex-2-enoic acid methyl ester 

Relevant articles and documents

Continuous flow biocatalytic resolutions of methyl sulfinylacetates

Product inhibition was encountered for some substrates in the resolution of methyl sulfinylacetates mediated by lipase Amano AK, so an apparatus to continually extract the carboxylate product was devised. This was applied to resolve some sulfoxides with h

A FACILE ROUTE TO HOMOCHIRAL SULFOXIDES

Biocatalytic resolution of methyl sulfinylacetates afford sulfoxides (R)-(1)-(6) in very high optical yields; the products have been used in a systematic study of the "SPAC" reaction, an asymmetric synthesis of γ-hydroxy-α,β-unsaturated esters.

Stereochemistry in the Knoevenagel Reaction of Methyl Arylsulphinylacetate and Aldehydes

The stereochemistry of the mechanism of the amine-catalyzed Knoevenagel reaction has been studied.Simple treatment of methyl arylsulphinylacetate (1) and aldehydes (2) with a catalytic amount of a secondary amine produced thermodynamically stable E-alkene

STEREOCHEMISTRY OF AMINE-CATALYZED KNOEVENAGEL REACTIONS

The amine-catalyzed Knoevenagel reactions of aldehydes and active methylene compounds containing two activating groups were found to involve many reversible steps, and the diastereomeric intermediary condensation compounds yielded thermodynamically stable products via carbanionic intermediates stablized and sterically affected by two activating groups.