844879-24-9

Basic information

• Product Name: 3-BROMO-3'-METHYLBENZOPHENONE
• Synonyms: 3-BROMO-3'-METHYLBENZOPHENONE
• CAS NO: 844879-24-9
• Molecular Formula: C14H11BrO
• Molecular Weight: 275.14
• Mol File: 844879-24-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 383.2°C at 760 mmHg
• Flash Point: 84.6°C
• Appearance: /
• Density: 1.375g/cm³
• Vapor Pressure: 4.47E-06mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: 3-BROMO-3'-METHYLBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-3'-METHYLBENZOPHENONE(844879-24-9)
• EPA Substance Registry System: 3-BROMO-3'-METHYLBENZOPHENONE(844879-24-9)

Safety Data

• Hazardous Substances Data: 844879-24-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H11BrO/c1-10-4-2-5-11(8-10)14(16)12-6-3-7-13(15)9-12/h2-9H,1H3

Upstream product

• 108-36-1 1,3-dibromobenzene 
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• 207681-67-2 N-methoxy-N-methyl-3-bromobenzamide 

Relevant articles and documents

Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors

A small library of 36 functionalized benzophenone thiosemicarbazone analogs has been prepared by chemical synthesis and evaluated for their ability to inhibit the cysteine proteases cathepsin L and cathepsin B. Inhibitors of cathepsins L and B have the potential to limit or arrest cancer metastasis. The six most active inhibitors of cathepsin L (IC50 50 > 10,000 nM). The most active analog in the series, 3-bromophenyl-2′-fluorophenyl thiosemicarbazone 1, also efficiently inhibits cell invasion of the DU-145 human prostate cancer cell line.