84488-53-9Relevant academic research and scientific papers
Pyridopyrimidines: Part I--Synthesis and Biological Activity of 2-Thiopyridopyrimidin-4(3H)-ones
Dave, C. G.,Shah, P. R.,Desai, V. B.,Srinivasan, S.
, p. 750 - 752 (2007/10/02)
3,5,7-Trisubstituted 2-thiopyridopyrimidin-4(3H)-ones (IV) have been synthesized by condensation of 2-amino-3-carbethoxy-4,6-disubstituted-pyridines (I) with a variety of isothiocyanates (II) followed by cyclization of the resultant thioureas (III).Some of the synthesized N1-substituted-N2--thioureas (III) and IV have been tested for antibacterial and antihistaminic activities.
