56162-64-2

Upstream product

• 60-29-7 diethyl ether 
• 27317-59-5 Ethyl 3-ethoxy-3-iminopropionate 
• 15397-33-8 3-Oxo-3-phenylpropanal 
• 115262-07-2 2-methyl-N-(1-phenylethylidene)propan-2-amine 
• 94-05-3 ethyl (ethoxymethylene)cyanoacetate 
• 24139-56-8 ethyl 2-cyano-5-phenyl-2,4-pentadienoate 
• 104-55-2 3-phenyl-propenal 
• 105-56-6 ethyl 2-cyanoacetate 
• 57508-48-2 carbethoxyacetamidine hydrochloride 
• 3623-15-2 phenyl propargyl ketone 
• 2318-25-4 ethyl 3-ethoxy-3-iminopropanoate hydrochloride 

Downstream Products

• 5175-12-2 2-amino-6-phenyl-nicotinic acid hydrazide 
• 100122-97-2 2-amino-6-phenyl-nicotinoyl azide 
• 84488-71-1 3-Cyclohexyl-7-phenyl-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 84488-69-7 7-Phenyl-2-thioxo-3-o-tolyl-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 84560-41-8 7-Phenyl-2-thioxo-3-p-tolyl-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 84488-70-0 7-Phenyl-2-thioxo-3-m-tolyl-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 84488-53-9 2-(3-Butyl-thioureido)-6-phenyl-nicotinic acid ethyl ester 
• 84488-67-5 3-Butyl-7-phenyl-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 84488-56-2 6-Phenyl-2-(3-m-tolyl-thioureido)-nicotinic acid ethyl ester 
• 84488-55-1 6-Phenyl-2-(3-o-tolyl-thioureido)-nicotinic acid ethyl ester 
• 84488-58-4 2-(3-Cyclohexyl-thioureido)-6-phenyl-nicotinic acid ethyl ester 
• 84488-52-8 6-Phenyl-2-(3-phenyl-thioureido)-nicotinic acid ethyl ester 
• 84488-54-0 2-(3-Benzyl-thioureido)-6-phenyl-nicotinic acid ethyl ester 
• 84488-57-3 6-Phenyl-2-(3-p-tolyl-thioureido)-nicotinic acid ethyl ester 

Relevant academic research and scientific papers

Microwave-Assisted Bohlmann-Rahtz Synthesis of Highly Substituted 2-Aminonicotinates

Microwave irradiation of 2-carbethoxyacetamidine and an ethynyl ketone under acidic or basic conditions in ethanol at 150 °C for 1.5 hours facilitated Bohlmann-Rahtz pyridine synthesis to give highly substituted ethyl 2-aminonicotinates with total regiocontrol and in reasonable to excellent yield, following purification by immobilization upon an acidic resin.

[5C + 1N] Annulation of 2,4-pentadienenitriles with hydroxylamine: A synthetic route to multi-substituted 2-aminopyridines

A facile and efficient synthetic route to multi-substituted 2-aminopyridines has been developed via a formal [5C + 1N] annulation of readily available 2,4-pentadienenitriles with hydroxylamine (NH2OH) under very mild conditions, which involves

A New Route to 2-Amino- or 2-Hydroxy-3-pyridinecarboxylic Acid Derivatives

Schiff's bases derived from ketones and t-butylamine (1) reacted with methyl methoxymethylenemalonate to give 2-hydroxy-3-pyridinecarboxylates.Similarly, treatment of 1 with ethoxymethylenemalononitrile gave 2-amino-3-pyridinecarbonitriles.Compounds 1 on reaction with ethyl 2-cyano-3-ethoxypropenoate afforded 2-amino-3-pyridinecarboxylates.