844891-09-4

Basic information

• Product Name: TERT-BUTYL 4-(4-FORMYLBENZYL)PIPERAZINE-1-CARBOXYLATE
• Synonyms: TERT-BUTYL 4-(4-FORMYLBENZYL)PIPERAZINE-1-CARBOXYLATE;4-(4-FORMYLBENZYL)PIPERAZINE, N1-BOC PROTECTED;4-(1-PIPERAZINYL)METHYLBENZALDEHYDE, N1-BOC PROTECTED;4-[(Piperazin-4-yl)methyl]benzaldehyde, N1-BOC protected;4-(4-Formylbenzyl)piperazine, N1-BOC protected 95%;N1-BOC-4-(4-FORMYLBENZYL)PIPERAZINE;tert-Butyl 4-(4-formylbenzyl)piperazine-1-carboxylate, 4-{[4-(tert-Butoxycarbonyl)piperazin-1-yl]methyl}benzaldehyde;4-(4-Formylbenzyl)piperazine,N1-BOCprotected95%
• CAS NO: 844891-09-4
• Molecular Formula: C₁₇H₂₄N₂O₃
• Molecular Weight: 304.38
• Mol File: 844891-09-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 57 °C
• Boiling Point: 420.3°C at 760 mmHg
• Flash Point: 208°C
• Appearance: /
• Density: 1.145g/cm³
• Vapor Pressure: 2.83E-07mmHg at 25°C
• Refractive Index: 1.563
• CAS DataBase Reference: TERT-BUTYL 4-(4-FORMYLBENZYL)PIPERAZINE-1-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 4-(4-FORMYLBENZYL)PIPERAZINE-1-CARBOXYLATE(844891-09-4)
• EPA Substance Registry System: TERT-BUTYL 4-(4-FORMYLBENZYL)PIPERAZINE-1-CARBOXYLATE(844891-09-4)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 844891-09-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H24N2O3/c1-17(2,3)22-16(21)19-10-8-18(9-11-19)12-14-4-6-15(13-20)7-5-14/h4-7,13H,8-12H2,1-3H3

Upstream product

• 52010-97-6 4-(hydroxylmethyl)benzaldehyde 
• 51359-78-5 4-(bromomethyl)benzaldehyde 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 73291-09-5 4-chloromethylbenzaldehyde 

Downstream Products

• 1095382-48-1 6-bromo-2-(4-(piperazin-1-ylmethyl)phenyl)-7-(4-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridine 
• 1095382-53-8 6-bromo-2-(4-(piperazin-1-ylmethyl)phenyl)-7-(4-(1-(pyridin-4-yl)ethyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridine 
• 1095382-58-3 6-bromo-2-(4-(piperazin-1-ylmethyl)phenyl)-7-(4-(1-(pyridin-3-yl)ethyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridine 
• 1095381-35-3 tert-butyl 4-(4-(6-bromo-7-(4-((5-methylisoxazol-3-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 942950-81-4 tert-Butyl 4-(4-(6-bromo-7-(4-((1-methyl-1H-imidazol-5-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 942950-79-0 tert-Butyl 4-(4-(6-bromo-7-(4-(thiazol-4-ylmethyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 942950-73-4 tert-Butyl 4-(4-(6-chloro-7-(4-((2-methylthiazol-4-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 942950-47-2 tert-Butyl 4-(4-(6-bromo-7-(4-((2-methylthiazol-4-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 1095380-83-8 tert-butyl 4-(4-(6-chloro-7-(4-(cyclobutylmethyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 1095382-62-9 tert-butyl 4-(4-(6-bromo-7-(4-((2-methylpyridin-4-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 1095380-88-3 tert-butyl 4-(4-(6-bromo-7-(4-((5-fluoropyridin-3-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 1095382-56-1 tert-butyl 4-(4-(6-bromo-7-(4-(1-(pyridin-3-yl)ethyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 1095382-51-6 tert-butyl 4-(4-(6-bromo-7-(4-(1-(pyridin-4-yl)ethyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 
• 1095382-46-9 tert-butyl 4-(4-(6-bromo-7-(4-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)benzyl)piperazine-1-carboxylate 

Relevant articles and documents

IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST

Disclosed herein is an imidazo [2, 1-f] [1, 2, 4] triazin-4-amine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof useful as a TLR7 agonist, and a pharmaceutical composition comprising the same. Also disclosed herein is a method of treating cancer using the imidazo [2, 1-f] [1, 2, 4] triazin-4-amine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof as TLR7 agonist.