84499-94-5Relevant academic research and scientific papers
Folate analogues. 21. Synthesis and antifolate and antitumor activities of N10-(cyanomethyl)-5,8-dideazafolic acid
Nair,Salter,Kisliuk,Gaumont,North,Sirotnak
, p. 605 - 607 (1983)
A close analogue of the antileukemic agent 5,8-dideaza-N10 propargylfolic acid (2) was synthesized by replacing the propargyl moiety of 2 with a cyanomethyl group. This compound, N10-(cyanomethyl)-5,8-dideazafolic acid (3), was evalu
