
Journal of Medicinal Chemistry p. 605 - 607 (1983)
Update date:2022-08-04
Topics:
Nair
Salter
Kisliuk
Gaumont
North
Sirotnak
A close analogue of the antileukemic agent 5,8-dideaza-N10 propargylfolic acid (2) was synthesized by replacing the propargyl moiety of 2 with a cyanomethyl group. This compound, N10-(cyanomethyl)-5,8-dideazafolic acid (3), was evalu
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(1983)