84500-68-5Relevant articles and documents
Design aspects of metal-free nitrogen-based catalysts and their influence on the yield in the Henry reaction
Yao, Qiong Ji,Khong, Duc Thinh,Gao, Qi,Judeh, Zaher M. A.
, p. 1793 - 1801 (2014/07/08)
Design aspects of metal-free nitrogen-based catalysts and their influence on the yield in the Henry reaction are disclosed. C 1-Symmetric, N,N-1,2-disposed amine-imine type catalysts were found to be most efficient. C 1-N,N-1,2-Disposed 1,2,3,4-tetrahydro-1,1′-biisoquinoline selectively and efficiently catalyzed the addition of nitromethane to α-keto esters and aldehydes giving exclusively the corresponding β-nitro alcohol adducts in excellent yields under very mild conditions. Georg Thieme Verlag Stuttgart New York.
Synthesis of 1-(Aminomethyl)-1,2,3,4-tetrahydroisoquinolines and Their Actions at Adrenoceptors in Vivo and in Vitro
Beaumont, David,Waigh, Roger D.,Sunbhanich, Methi,Nott, Michael W.
, p. 507 - 515 (2007/10/02)
An improved synthesis of 1-(aminomethyl)-1,2,3,4-tetrahydroisoquinolines has been developed by using aluminum hydride reduction of 1-cyano-1,2,3,4-tetrahydroisoquinolines.Three 1-(aminomethyl)-6,7-dihydroxytetrahydroisnolines