845267-80-3 Usage
Uses
Used in Pharmaceutical Synthesis:
1-Boc-5-Ethyl-2,4-dioxopiperidine is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into the structures of potential therapeutic agents. Its presence in the molecular framework can influence the pharmacokinetic and pharmacodynamic properties of the final drug, enhancing their efficacy and safety profiles.
Used in Agrochemical Development:
In the agrochemical industry, 1-Boc-5-Ethyl-2,4-dioxopiperidine serves as a precursor in the development of new pesticides and other crop protection agents. Its chemical properties allow for the creation of molecules with specific modes of action against pests and diseases, contributing to more effective and targeted agricultural solutions.
Used in the Preparation of Antitumor Agents:
1-Boc-5-Ethyl-2,4-dioxopiperidine is utilized as a building block in the preparation of potential antitumor agents. Its structural elements can be modified to target specific cancer cells or pathways, offering a route to develop new cancer treatments with improved selectivity and reduced side effects.
Used in the Preparation of Antimalarial Agents:
1-Boc-5-Ethyl-2,4-dioxopiperidine is also used in the synthesis of antimalarial drugs, where its unique structure can be leveraged to create molecules that target the Plasmodium parasites responsible for malaria. The development of new antimalarial agents is crucial for combating drug-resistant strains and improving global health outcomes.
Overall, 1-Boc-5-Ethyl-2,4-dioxopiperidine's applications span across various fields, highlighting its importance in the creation of bioactive molecules with potential therapeutic and agricultural benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 845267-80-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,2,6 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 845267-80:
(8*8)+(7*4)+(6*5)+(5*2)+(4*6)+(3*7)+(2*8)+(1*0)=193
193 % 10 = 3
So 845267-80-3 is a valid CAS Registry Number.
845267-80-3Relevant academic research and scientific papers
N-substituted pyrrolopyridinones active as kinase inhibitors
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Page/Page column 18, (2010/11/27)
Compounds represented by formula (I) wherein A, R1, R2, R3, R4, R5, and R6 are as defined in the specification, pharmaceutical compositions thereof, and methods of use thereof.
Regioselective γ-alkylation of tert-butyl 2,4-dioxopiperidine-1- carboxylate
Orsini, Paolo,Maccario, Alessandro,Colombo, Nicoletta
, p. 3185 - 3190 (2008/04/03)
A method for the regioselective γ-alkylation of N-Boc protected piperidine-2,4-dione is reported. The use of a wide variety of electrophiles demonstrates the robustness of the procedure. The reaction offers facile access to synthetically useful derivatives. A mechanistic hypothesis is given, explaining the essential role played by the lithium counter-ion. Georg Thieme Verlag Stuttgart.
PYRIDYLPYRROLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
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Page/Page column 43, (2010/02/10)
Pyridylpyrrole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treat
PYRIMIDYLPYRROLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
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Page/Page column 34, (2010/02/10)
Pyrimidylpyrrole derivatives of formula (1) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be
