84529-13-5Relevant academic research and scientific papers
Pd/C-catalyzed reductive mono-N-alkylation of nitrophenol derivatives in one-pot way
Jin, Zhonghao,Li, Dao,Wang, Xingyi,Lu, Guanzhong
experimental part, p. 16 - 20 (2010/09/07)
A range of different nitrophenol derivatives were converted in one-pot to the corresponding secondary alkyl aminophenols in good to excellent yields by using ketones as alkyl source and hydrogen over 10 wt% Pd/C as reducing agent. In all examples, except for one, the secondary amine was the sole alkylation product isolated. When aldehydes were used as alkyl source, the corresponding tertiary amine as a sole alkylation product was isolated.
Microwave-assisted one-pot regioselective synthesis of 2-alkyl-3,4-dihydro- 3-oxo-2H-1,4-benzoxazines
Dai, Wei-Min,Wang, Xuan,Ma, Chen
, p. 6879 - 6885 (2007/10/03)
A protocol for regioselective one-pot synthesis of 2-alkyl-3,4-dihydro-3- oxo-2H-1,4-benzoxazines under controlled microwave heating has been developed. Starting from commercially available 2-aminophenols, a base-mediated regioselective O-alkylation took
