84538-40-9 Usage
Uses
Used in Pharmaceutical Industry:
2,4-DiMethoxy-5H-pyrrolo[3,2-d]pyriMidine is used as a pharmaceutical candidate for its potential anti-inflammatory, analgesic, and antitumor properties. Its unique structure and methoxy substitutions may contribute to its biological activities, making it a promising compound for the development of new medications.
Used in Organic Synthesis:
2,4-DiMethoxy-5H-pyrrolo[3,2-d]pyriMidine is used as a building block in the synthesis of various organic compounds and pharmaceuticals. Its versatile chemical structure allows for further functionalization and modification, enabling the creation of new molecules with potential applications in different industries.
Used in Medicinal Chemistry Research:
2,4-DiMethoxy-5H-pyrrolo[3,2-d]pyriMidine is utilized in medicinal chemistry research to explore its potential as a lead compound for drug discovery. Its biological activities and chemical properties are being investigated to understand its mechanism of action and to optimize its therapeutic potential.
Used in Drug Development:
2,4-DiMethoxy-5H-pyrrolo[3,2-d]pyriMidine is employed in drug development as a starting point for the design and synthesis of new pharmaceutical agents. Its unique structure and potential biological activities make it a valuable compound for the development of innovative treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 84538-40-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,3 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 84538-40:
(7*8)+(6*4)+(5*5)+(4*3)+(3*8)+(2*4)+(1*0)=149
149 % 10 = 9
So 84538-40-9 is a valid CAS Registry Number.
84538-40-9Relevant academic research and scientific papers
Cupps, Thomas L.,Wise, Dean S.,Townsend, Leroy B.
, p. 4759 - 4762 (1982)
The synthesis of 2,4-dimethoxypyrrolopyrimidine (4) is described.This facile, 3-step synthesis involves the bromination of 2,4-dimethoxy-6-methyl-5-nitropyrimidine (1), and the subsequent conversion of compound 1 into compound 4.
Condensed heteroaromatic ring systems. XXI. Synthesis of pyrrolo[2,3-d]pyrimidines and pyrrolo[3,2-d]pyrimidines
Sakamoto,Satoh,Kondo,Yamanaka
, p. 81 - 86 (2007/10/02)
Pyrrolo[2,3-d]pyrimidines and pyrrolo[3,2-d]pyrimidines were synthesized in high yields by the palladium-catalyzed reaction of 4-acetylamino-5-bromopyrimidines and 5-acetylamino-4-iodopyrimidines with (Z)-1-ethoxy-2-(tributylstannyl)ethene followed by cyclization under acidic conditions.
Synthetic Strategies toward the Synthesis of 2,4-Dimethoxypyrrolopyrimidine
Cupps, Thomas L.,Wise, Dean S.,Townsend, Leroy B.
, p. 1060 - 1064 (2007/10/02)
Two approaches to prepare 2,4-dimethoxypyrrolopyrimidine (1) are described. 2,4-Dimethoxy-6-methyl-5-nitropyrimidine (2) was converted to 6-(cyanomethyl)-2,4-dimethoxy-5-nitropyrimidine (6) in two steps.Subsequent catalytic hydrogenation of 6 produced 1.In a second approach, 2 was formylated, giving rise to 6--2,4-dimethoxy-5-nitropyrimidine (7).Hydrogenation of 7 resulted in the formation of 1.Reduction of 2 provided 5-amino-2,4-dimethoxy-6-methylpyrimidine (10).Reaction of compound 10 with triethyl orthoformate produced 2,4-dimethoxy-5--6-methylpyrimidine (11).Reaction of 11 with lithium diisopropylamide gave 2,4-dimethoxy-5-isocyano-6-methylpyrimidine (12).
