84539-48-0 Usage
General Description
2,4-dibromo-5-methoxylpyridine is a compound with the molecular formula C6H4Br2NO. It is a derivative of pyridine with two bromine atoms and one methoxy group attached to the carbon atoms in the aromatic ring. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in organic chemistry and has potential applications in material science. 2,4-dibromo-5-methoxylpyridine is known to have low solubility in water and is considered to be harmful if ingested, inhaled, or comes in contact with the skin or eyes.
Check Digit Verification of cas no
The CAS Registry Mumber 84539-48-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,3 and 9 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 84539-48:
(7*8)+(6*4)+(5*5)+(4*3)+(3*9)+(2*4)+(1*8)=160
160 % 10 = 0
So 84539-48-0 is a valid CAS Registry Number.
84539-48-0Relevant articles and documents
Bromination of Some Pyridine and Diazine N-Oxides
Paudler, William W.,Jovanovic, Misa V.
, p. 1064 - 1069 (2007/10/02)
Selected monosubstituted pyridines, pyrazines, pyrimidines, and their N-oxides, having an electron-donating substituent, were successfully brominated under very mild conditions.The N-oxide function itself is not sufficient to cause these ?-deficient systems to undergo electrophilic aromatic halogenation.Only strongly electron-donating substituents (amino groups) activate the heterocyclic nucleus toward bromination.These substituents direct the electrophilic substitution ortho/para to them with or without the N-oxide group present.Pyridine and diazines with moderately activating substituents such as alkoxy groups are brominated only when their ortho/para activation is augmented by the activation of the N-oxide funtion.Failure to brominate 5-methoxypyrimidine 1-oxide may well reflect the greater ? deficiency of the pyrimidine ring.
