84545-70-0 Usage
General Description
N-((4-Chloromethyl)-2-thiozolyl)guanidine hydrochloride is a chemical compound with the molecular formula C6H8ClN3S.HCl. It is a guanidine derivative and is commonly used as an antihypertensive and vasodilator agent. N-((4-Chloromethyl)-2-thiozolyl)guanidine hydrochloride has been studied for its potential therapeutic effects on hypertension and cardiovascular diseases. It functions by blocking the activity of calcium channels in smooth muscle cells, leading to relaxation and dilation of blood vessels, which in turn lowers blood pressure. Additionally, it has shown potential as a therapeutic agent for other conditions such as migraines, diabetic neuropathy, and hypoxic-ischemic injury. Overall, N-((4-Chloromethyl)-2-thiozolyl)guanidine hydrochloride has been of interest for its pharmacological properties and potential applications in the treatment of various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 84545-70-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,5,4 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 84545-70:
(7*8)+(6*4)+(5*5)+(4*4)+(3*5)+(2*7)+(1*0)=150
150 % 10 = 0
So 84545-70-0 is a valid CAS Registry Number.
84545-70-0Relevant articles and documents
ONE-POT PREPARATION OF S-(GUANIDINO-4-YL-METHYL)-ISOTHIOUREA DIHYDROCHORIDE
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Page/Page column 5, (2010/02/10)
The invention relates to a new one pot preparation of N-[[4-(amino iminoethyl)thio]methyl]-2-thiozolyl]-guanidine dihydrochloride of formula (IV), by the reaction of 1, 3idiochloroacetone of formula (I) with gunadinothiourea of formula (II) and reacting the compound formed insitu (formula-III) with thiourea.
