845513-02-2Relevant academic research and scientific papers
The total synthesis of gambierol
Johnson, Henry W. B.,Majumder, Utpal,Rainier, Jon D.
, p. 848 - 849 (2005)
This communication describes the total synthesis of the marine polyether toxin, gambierol. This work couples our iterative C-glycoside/enol ether-olefin metathesis strategy to the subunits with a unique olefin metathesis/carbonyl olefination reaction to bring the subunits together. Copyright
Total synthesis of gambierol: Subunit coupling and completion
Johnson, Henry W. B.,Majumder, Utpal,Rainier, Jon D.
, p. 1747 - 1753 (2008/02/02)
The preceding manuscript detailed our synthesis of the gambierol A-C and F-H ring precursors. Reported herein is a description of the coupling of the two precursors and the conversion of the coupled material into gambierol. Coupling of the subunits involv
