84553-76-4Relevant academic research and scientific papers
Synthesis of the core structure of the lipoteichoic acid of streptococcus pneumoniae
Pedersen, Christian Marcus,Figueroa-Perez, Ignacio,Boruwa, Joshodeep,Lindner, Buko,Ulmer, Artur J.,Zaehringer, Ulrich,Schmidt, Richard R.
experimental part, p. 12627 - 12641 (2011/02/21)
Streptococcus pneumoniae LTA is a highly complex glycophospholipid that consists of nine carbohydrate residues: three glucose, two galactosamine and two 2-acetamino-4-amino-2,4,6-trideoxygalactose (AATDgal) residues that are each differently linked, one r
Synthesis of 8-azidooctyl glycoside derivatives of the O-chain repeating unit of Escherichia coli O9a lipopolysaccharide and a methylated analog
Hou, Dianjie,Skogman, Fredrik,Lowary, Todd L.
, p. 1778 - 1789 (2008/12/21)
Described is the synthesis of 8-azidooctyl glycoside derivatives of the Escherichia coli serotype O9a O-chain tetrasaccharide repeating unit and the terminal tetrasaccharide motif in this polysaccharide, which contains a methyl group on O-3 of the distal mannopyranose residue. The assembly of these compounds involved the sequential addition of monosaccharide residues from the reducing to the nonreducing end of the molecule using glycosyl trichloroacetimidate donors. Both compounds were initially prepared as p-methoxyphenyl glycosides, which were converted to the corresponding 8-azidooctyl derivatives at a late stage in the synthesis.
Sequential one-pot glycosidations catalytically promoted: Unprecedented strategy in oligosaccharide synthesis for the straightforward assemblage of the antitumor PI-88 pentasaccharide
Valerio, Silvia,Pastore, Antonello,Adinolfi, Matteo,Iadonisi, Alfonso
, p. 4496 - 4503 (2008/09/21)
(Chemical Equation Presented) The pentasaccharide sequence of the most active components of the antitumor drug PI-88, currently in phase II clinical trial, has been rapidly assembled in high overall yield and in only three steps starting from three monosa
METHOD FOR TREATING GALABIOSE-BINDING BACTERIA INFECTIONS
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, (2008/06/13)
A method for treating infections caused by galabiose-binding bacteria using galabiose derivatives modified at the 3 and anomeric positions. The galabiose-derivatives and compositions of some are also disclosed
A NOVEL PROCEDURE FOR THE PREPARATION OF 1-OH SUGAR DERIVATIVES USING 2-METHOXYETHYL GLYCOSIDES
Morishima, Naohiko,Koto, Shinkiti,Kanemitsu, Kumi,Zen, Shonosuke
, p. 1189 - 1190 (2007/10/02)
Treatment of benzyl-protected 2-methoxyethyl glycopyranosides with titanium tetrachloride followed by hydrolysis provides a new method for the preparation of the corresponding 1-OH sugar derivatives.The present method is shown to be useful for the prepara
