845531-08-0Relevant academic research and scientific papers
STRAIGHT-CHAIN AND BRANCHED-CHAIN LIPID COMPOUNDS AS SELECTIVE INHIBITORS OF CYCLOOXYGENASE-2, ANTI-INFLAMMATORY AGENTS, AND ANTI-CANCER AGENTS
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Page/Page column 13, (2008/06/13)
Unique branched-chain lipid compounds are disclosed as selective COX-2 inhibitors, which are derivatives of a branched-chain fatty amine or a branched-chain fatty amide, or a pharmaceutically acceptable salt thereof. The compounds can be used for osteoarthritis and rheumatoid arthritis as anti-inflammatory agents, in addition to treating and preventing cancer. Straight-chain analogs of the branched-chain lipid compounds provide similar uses.
