845548-50-7Relevant academic research and scientific papers
Mechanisms of cyclisation of indolo oxime ethers. Part 2: Formation of?ethyl 6,8-dimethoxypyrazolo[4,5,1-hi]indole-5-carboxylates
Clayton, Kylie A.,Black, David StC.,Harper, Jason B.
, p. 3183 - 3189 (2008/09/19)
The cyclisation of a series of ethyl 3′-phenyl-4′,6′-dimethoxyindol-7′-yl-2-(hydroxyimino)acetates was investigated using 1H NMR spectroscopy to determine the mechanism of formation of the corresponding ethyl 6,8-dimethoxypyrazolo[4,5,1-hi]indo
Mechanisms of cyclisation of indolo oxime ethers I. Formation of ethyl 9,11-dimethoxy indolo[2,3-c]quinoline-6-carboxylates
Clayton, Kylie A.,Black, David StC.,Harper, Jason B.
, p. 10615 - 10621 (2008/02/12)
The cyclisation of a series of ethyl 3′-aryl-4′,6′-dimethoxyindol-2′-yl-2-(hydroxyimino)acetates was investigated using 1H NMR spectroscopy to determine the mechanism of formation of the corresponding ethyl 9,11-dimethoxy indolo[2,3-c]quinoline
Reaction of some 4,6-dimethoxyindoles with nitric acid: Nitration and oxidative dimerisation
Keawin, Tinnagon,Rajviroongit, Shuleewan,Black, David Stc.
, p. 853 - 861 (2007/10/03)
A range of 3-substituted-4,6-dimethoxyindoles bearing electron-withdrawing groups in either the 2- or 7-position, can be nitrated using nitric acid in acetonitrile, to give 7-nitro and 2-nitro-indoles, respectively. Those without electron-withdrawing groups undergo oxidative dimerisation at C7, if 2,3-disubstituted, and at C2, if N-methylated and unsubstituted at C2. Some 3-substituted-4,6-dimethoxyindoles can be nitrated using nitric acid in acetonitrile, to give 7-nitro and 2-nitro-indoles. Some undergo oxidative dimerisation at C7, if 2,3-disubstituted, and at C2, if N-methylated and unsubstituted at C2.
