845616-10-6 Usage
General Description
1-[2-Fluoro-4-(methylsulfonyl)phenyl]piperazine is a compound consisting of a piperazine ring and a phenyl ring with a fluorine atom and a methylsulfonyl group attached to it. This chemical is commonly used as a pharmaceutical intermediate, and it has been studied for its potential therapeutic applications, particularly in the field of medicinal chemistry. It has been reported to have various biological activities, including as an antagonist at serotonin receptors, and it has also been investigated for its potential use in the treatment of certain neurological and psychiatric disorders. Additionally, this chemical has been the subject of research for its potential use in the development of new drugs for the treatment of various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 845616-10-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,6,1 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 845616-10:
(8*8)+(7*4)+(6*5)+(5*6)+(4*1)+(3*6)+(2*1)+(1*0)=176
176 % 10 = 6
So 845616-10-6 is a valid CAS Registry Number.
845616-10-6Relevant articles and documents
2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists
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Page 23, (2008/06/13)
Compounds having the structural formula I or a pharmaceutically acceptable salt thereof, wherein R is R1, R2, R3, R4 and R5 are H, alkyl or alkoxyalkyl; R6 is H, alkyl, hydroxyalkyl or —CH2F; R7, R8 and R9 are H, alkyl, alkoxy, alkylthio, alkoxyalkyl, halo or —CF3; and Z is optionally substituted aryl, heteroaryl or heteroaryl-alkyl are disclosed. Also disclosed is the use of compounds of formula I in the treatment of central nervous system diseases, in particular Parkinson's disease, alone or in combination with other agents for treating Parkinson's disease, and pharmaceutical compositions comprising them.
