845620-26-0

Basic information

• Product Name: Propanedioic acid, [(4-methylphenyl)sulfonyl]-, methyl [(4S)-4-(1-methylethenyl)-1-cyclohexen-1-yl]methyl ester
• CAS NO: 845620-26-0
• Molecular Formula: C21H26O6S
• Molecular Weight: 406.5
• Mol File: 845620-26-0.mol

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [(4-methylphenyl)sulfonyl]-, methyl [(4S)-4-(1-methylethenyl)-1-cyclohexen-1-yl]methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [(4-methylphenyl)sulfonyl]-, methyl [(4S)-4-(1-methylethenyl)-1-cyclohexen-1-yl]methyl ester(845620-26-0)
• EPA Substance Registry System: Propanedioic acid, [(4-methylphenyl)sulfonyl]-, methyl [(4S)-4-(1-methylethenyl)-1-cyclohexen-1-yl]methyl ester(845620-26-0)

Safety Data

• Hazardous Substances Data: 845620-26-0(Hazardous Substances Data)

Upstream product

• 845620-16-8 Malonic acid (S)-4-isopropenyl-cyclohex-1-enylmethyl ester methyl ester 
• 455-16-3 p-toluenesulfonyl fluoride 

Relevant articles and documents

A [3,3]-sigmatropic process catalysed by acetate. The decarboxylative Claisen rearrangement

Allylic tosylacetates and tosylmalonates undergo acetate-catalysed decarboxylative Claisen rearrangement in the presence of N,O-bis(trimethylsilyl) acetamide. The homoallylic sulfones formed in these transformations correspond to the products of regiospecific allylation of sulfone-stabilised carbanions. A mechanistic rationale is proposed.

Decarboxylative Claisen rearrangement reactions of allylic tosylmalonate esters

(Chemical Equation Presented) Two different combinations of silylating agent and base are used for one-pot [3,3]-sigmatropic rearrangement- decarboxylation reactions of tosylmalonic mono(allylic) esters under mild conditions, providing the products of formal regiospecific allylation of methyl tosylacetate at the more substituted allylic terminus.