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(2S)-1-[(2R)-4-Benzoyl-2-methyl-piperazin-1-yl]-2-(quinolin-5-yloxy)-propan-1-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

845654-02-6

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845654-02-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 845654-02-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,5,6,5 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 845654-02:
(8*8)+(7*4)+(6*5)+(5*6)+(4*5)+(3*4)+(2*0)+(1*2)=186
186 % 10 = 6
So 845654-02-6 is a valid CAS Registry Number.

845654-02-6Relevant articles and documents

Design and optimisation of potent gp120-CD4 inhibitors

Tran, Thien-Duc,Adam, Fiona M.,Calo, Frederick,Fenwick, David R.,Fok-Seang, Juin,Gardner, Iain,Hay, Duncan A.,Perros, Manos,Rawal, Jaiessh,Middleton, Donald S.,Parkinson, Tanya,Pickford, Christopher,Platts, Michelle,Randall, Amy,Stephenson, Peter T.,Vuong, Hannah,Williams, David H.

scheme or table, p. 5250 - 5255 (2010/03/24)

The synthesis and structure-activity relationship of a series of novel gp120-CD4 inhibitors are described. Pharmacokinetic studies and antiviral spectrum assessment of lead compounds led to the identification of compound 36, a potent gp120-CD4 inhibitor w

Piperazine derivatives

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Page/Page column 41, (2010/02/10)

This invention relates to a compound of formula (I) or pharmaceutically acceptable salts, solvates or derivatives thereof, wherein R1 to R5 are defined in the description, and to processes for the preparation thereof, intermediates used in their preparation, compositions containing them and the uses of such derivatives. The compounds of the present invention inhibit the interaction of gp120 with CD4 and are therefore of use in the treatment of HIV, a retroviral infection genetically related to HIV, or AIDS.

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