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357263-39-9

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357263-39-9 Usage

General Description

(R)-2-Methyl-4-benzoylpiperazine is a chemical compound with the molecular formula C13H16N2O. It is a piperazine derivative with a benzoyl group and a methyl substituent attached to the piperazine ring. (R)-2-METHYL-4-BENZOYLPIPERAZINE has been studied for its potential pharmacological activity, particularly in the field of medicinal chemistry and drug development. (R)-2-Methyl-4-benzoylpiperazine has been investigated for its potential as a serotonin reuptake inhibitor and for its potential as an antipsychotic agent. It is a chiral compound, and the (R)-enantiomer may have different biological activity compared to the (S)-enantiomer, making it important for pharmaceutical research and development. Overall, (R)-2-Methyl-4-benzoylpiperazine is a compound of interest in the field of medicinal chemistry due to its potential pharmacological properties.

Check Digit Verification of cas no

The CAS Registry Mumber 357263-39-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,7,2,6 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 357263-39:
(8*3)+(7*5)+(6*7)+(5*2)+(4*6)+(3*3)+(2*3)+(1*9)=159
159 % 10 = 9
So 357263-39-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N2O/c1-10-9-14(8-7-13-10)12(15)11-5-3-2-4-6-11/h2-6,10,13H,7-9H2,1H3/t10-/m1/s1

357263-39-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-2-METHYL-4-BENZOYLPIPERAZINE

1.2 Other means of identification

Product number -
Other names (R)-1-BENZOYL-3-METHYLPIPERAZINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:357263-39-9 SDS

357263-39-9Relevant articles and documents

ANNELATED PYRIDAZINES FOR THE TREATMENT OF TUMORS DRIVEN BY INAPPROPRIATE HEDGEHOG SIGNALLING

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Page/Page column 69, (2009/04/25)

The present invention relates generally to compounds represented in Formula (I), pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.

PIPERAZINE DERIVATIVES

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Page/Page column 30, (2008/06/13)

The present invention relates to a crystalline form of 5-{(1S)-2-[(2R)-4-benzoyl-2-methyl-piperazin-1-yl]-1-methyl-2-oxo-ethoxy}-4-methoxy-pyridine-2-carboxylic acid methylamide, processes for the preparation thereof, compositions containing the crystalli

Discovery of 4-benzoyl-1-[(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2-(R) -methylpiperazine (BMS-378806): A novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions

Wang, Tao,Zhang, Zhongxing,Wallace, Owen B.,Deshpande, Milind,Fang, Haiquan,Yang, Zheng,Zadjura, Lisa M.,Tweedie, Donald L.,Huang, Stella,Zhao, Fang,Ranadive, Sunanda,Robinson, Brett S.,Gong, Yi-Fei,Ricarrdi, Keith,Spicer, Timothy P.,Deminie, Carol,Rose, Ronald,Wang, Hwei-Gene Heidi,Blair, Wade S.,Shi, Pei-Yong,Lin, Pin-Fang,Colonno, Richard J.,Meanwell, Nicholas A.

, p. 4236 - 4239 (2007/10/03)

Indole derivative 1 interferes with the interaction of the HIV surface protein gp120 with the host cell receptor CD4. The 4-fluoro derivative 2 exhibited markedly enhanced potency and was bioavailable in the rat, dog, and cynomolgus monkey when administered orally as a solution formulation. However, aqueous suspensions of 2 were poorly bioavailable, indicative of dissolution-limited absorption. The 7-azaindole derivative 3, BMS-378806, exhibited improved pharmaceutical properties while retaining the HIV-1 inhibitory profile of 2.

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